Acetylcysteine (Acetyphil) 600mg Powder For Oral Solution Sachets 10's

Indications:

Treatment of respiratory affections characterized by thick and viscous hypersecretions: acute and chronic bronchitis and its exacerbations, pulmonary emphysema, mucoviscidosis and bronchiectasis.

Certainly! Here's an overview of Acetylcysteine (Acetyphil) 600mg Powder for Oral Solution Sachets 10's:

Product Description:

Acetylcysteine (Acetyphil) 600mg Powder for Oral Solution is a mucolytic agent used primarily to help break down mucus in the airways, making it easier to clear the mucus from the lungs. It contains Acetylcysteine, a derivative of the amino acid cysteine, which works by breaking the disulfide bonds in mucus proteins, reducing the viscosity and helping to thin the mucus. This improves mucus clearance and relieves symptoms related to excessive mucus production.

The product comes in sachets containing 600 mg of Acetylcysteine in powder form, designed to be dissolved in water to create an oral solution. Each box contains 10 sachets.

Indications:

Acetylcysteine (Acetyphil) is used for the following conditions:

• Chronic obstructive pulmonary disease (COPD): To help clear mucus and reduce the viscosity of the mucus in the airways.

• Bronchitis (acute and chronic): To alleviate symptoms of excessive mucus production and help in clearing the airways.

• Cystic fibrosis: To reduce mucus viscosity and improve mucus clearance.

• Pneumonia: As an adjunct to other treatments to manage symptoms of excessive mucus production.

• Acetaminophen (paracetamol) overdose: Acetylcysteine is the antidote used to treat acetaminophen toxicity, protecting the liver from damage by replenishing glutathione levels.

Dosage:

The typical dosage of Acetylcysteine (Acetyphil) 600mg depends on the specific condition being treated:

• For Respiratory Conditions (COPD, Chronic Bronchitis, Cystic Fibrosis):

  • Adults: The usual dose is 600 mg once or twice daily, depending on the severity of the condition. The powder from one sachet should be dissolved in a glass of water and taken orally.

• For Acute Bronchitis:

  • Adults: Typically, 600 mg of Acetylcysteine is taken once or twice a day.

• For Acetaminophen Overdose:

  • Initial Dose: The typical starting dose is 140 mg/kg as a loading dose, followed by 70 mg/kg every 4 hours for a total of 17 doses (given over 72 hours).

  • Note: This dosage is specific to acetaminophen overdose and should only be administered in a clinical setting.

Note: Always follow your healthcare provider's recommendations regarding dosage, as it may vary based on individual health status and treatment goals.

Side Effects:

Common side effects of Acetylcysteine (Acetyphil) may include:

• Gastrointestinal issues such as:

  • Nausea, vomiting

  • Abdominal discomfort or pain

  • Diarrhea

  • Heartburn

• Allergic reactions (rare), including:

  • Rash, hives, itching

  • Swelling of the lips, face, or throat (severe cases may lead to anaphylaxis)

• Headache

• Dizziness

• Fever (in rare cases)

Serious side effects (though rare) may include:

• Severe allergic reactions, including anaphylaxis (difficulty breathing, swelling, dizziness, or fainting)

• Severe gastrointestinal reactions, such as bleeding or ulcers (in rare instances)

If you experience any severe reactions or difficulty breathing, seek medical help immediately.

Contraindications:

Acetylcysteine (Acetyphil) should not be used in the following situations:

• Hypersensitivity: If you have a known allergy to Acetylcysteine or any of the ingredients in the product.

• Severe respiratory distress: Caution is advised in patients who are acutely ill or unable to clear secretions effectively.

• Peptic Ulcer Disease: Acetylcysteine should be used cautiously in patients with a history of gastrointestinal ulcers, as it may exacerbate symptoms.

• Asthma: Although generally safe for most people with asthma, some patients may experience bronchospasm or increased airway irritation. It should be used with caution in asthmatic patients, particularly those with a history of wheezing or shortness of breath.

Precautions:

• Asthma: As noted above, caution is required in asthmatic patients, as Acetylcysteine may increase airway irritation or trigger bronchospasm in sensitive individuals. In such cases, it is advised to monitor patients closely.

• Gastrointestinal issues: Patients with a history of peptic ulcer disease or gastrointestinal bleeding should use Acetylcysteine cautiously, as it can irritate the stomach.

• Liver or Kidney Disease: Use with caution in patients with severe liver or kidney problems, and only under medical supervision if needed.

• Pregnancy and Breastfeeding: Acetylcysteine is generally considered safe for use during pregnancy and breastfeeding when prescribed by a healthcare provider. However, it should only be used when necessary, and any concerns should be discussed with a healthcare provider.

• Concurrent Medications: Always inform your healthcare provider of any other medications you are taking, as Acetylcysteine may interact with other drugs, especially certain medications used in the treatment of respiratory conditions or liver disease.

Storage:

• Store Acetylcysteine (Acetyphil) 600mg Powder for Oral Solution at room temperature, away from heat and moisture.

• Keep the sachets in their original packaging to protect them from light.

• Keep out of reach of children.

This information provides a general overview of Acetylcysteine (Acetyphil) 600mg Powder for Oral Solution Sachets 10's. Always consult with a healthcare provider for specific dosage instructions and medical advice tailored to your health condition.