Amoxicillin (Axmel) 125mg/5ml Powder for Suspension Penicillin 60ml

125mg/5ml Powder for Suspension Penicillin

Amoxicillin (Axmel) 125mg/5ml Powder for Suspension Penicillin 60ml

Product Description:

Amoxicillin (Axmel) 125mg/5ml is a penicillin-class antibiotic in the form of a powder for suspension. It is used to treat a variety of bacterial infections, such as ear infections, respiratory infections, skin infections, and urinary tract infections. The product comes in a 60ml bottle of powder, which, when mixed with water, forms a suspension for oral administration.

Active Ingredient: Amoxicillin 125mg per 5ml.

Form: Oral suspension, ideal for children or individuals who have difficulty swallowing tablets.

Indications:

Amoxicillin (Axmel) is used for the treatment of bacterial infections, including but not limited to:

1. Upper Respiratory Tract Infections:

   • Sinusitis, tonsillitis, pharyngitis.

   • Acute otitis media (middle ear infections).

2. Lower Respiratory Tract Infections:

   • Bronchitis, pneumonia.

3. Urinary Tract Infections (UTIs):

   • Cystitis, pyelonephritis.

4. Skin and Soft Tissue Infections:

   • Impetigo, cellulitis, abscesses.

5. Gastrointestinal Infections:

   • Helicobacter pylori eradication as part of combination therapy for peptic ulcer disease (in some cases).

6. Dental Infections:

   • Abscesses or infections following dental procedures.

7. Prevention of Endocarditis:

   • In patients undergoing certain types of surgery (e.g., dental procedures) with risk of infection.

Dosage and Administration:

Amoxicillin (Axmel) 125mg/5ml suspension should be taken according to the prescribed dosage based on the patient's age, weight, and the severity of the infection. It is essential to follow the dosing instructions provided by your healthcare provider.

General Dosage Guidelines:

• For Children:

  • Age 2-5 years: Typically, 5 mL (125mg) every 8 hours.

  • Age 6-12 years: 10 mL (250mg) every 8 hours or as directed by the doctor.

• For Adults:

  • The typical dose for adults may range from 250mg to 500mg every 8 hours depending on the infection's severity.

  • For more severe infections, higher doses may be prescribed, but the specific dosage should always be determined by a healthcare provider.

Instructions:

1. Shake the bottle well before use to ensure the suspension is evenly mixed.

2. Use the provided measuring device (dropper or spoon) to measure the correct dose.

3. Administer orally. It can be taken with or without food.

4. Complete the full course of antibiotics, even if symptoms improve, to avoid resistance.

Side Effects:

While Amoxicillin (Axmel) is generally well-tolerated, some side effects can occur. Common and serious side effects include:

1. Common Side Effects:

   • Gastrointestinal discomfort: nausea, vomiting, diarrhea, stomach upset.

   • Skin rash: Sometimes, a mild rash may develop.

   • Headache: Occasional headaches may occur.

2. Serious Side Effects (Rare):

   • Severe allergic reactions: Swelling of the face, lips, throat, or difficulty breathing. If these occur, seek emergency medical help.

   • Severe skin reactions: Red, blistered, or peeling skin.

   • Liver problems: Jaundice (yellowing of the skin or eyes), unusual tiredness, dark urine.

   • Clostridium difficile-associated diarrhea: A serious intestinal condition causing severe diarrhea.

   • Blood disorders: Unusual bruising, bleeding, or sore throat can indicate blood issues (e.g., low white blood cells or platelets).

3. Signs of Overdose:

   • Nausea, vomiting, and diarrhea.

   • Severe abdominal cramps or tenderness.

   • Seek immediate medical attention if an overdose is suspected.

Contraindications:

Amoxicillin (Axmel) should not be used in the following cases:

1. Hypersensitivity to Penicillin:

   • If the patient has a known allergy to amoxicillin, other penicillins, or cephalosporin antibiotics, they should not take this medication.

2. History of Severe Allergic Reactions:

   • Patients with a history of severe allergic reactions (e.g., anaphylaxis) to penicillin or other beta-lactam antibiotics should avoid amoxicillin.

3. Mononucleosis:

   • Amoxicillin should not be used in patients with infectious mononucleosis (also known as "mono" or glandular fever), as it can lead to a higher risk of developing a skin rash.

4. Severe Renal Impairment:

   • In patients with severely impaired kidney function, the dosage may need to be adjusted, or an alternative antibiotic should be considered.

Precautions:

• Renal Impairment: Caution is required in patients with kidney disease or renal impairment. Dose adjustments may be necessary.

• Gastrointestinal Issues: Patients with a history of gastrointestinal disease, especially colitis, should use amoxicillin with caution.

• Prolonged Use: Prolonged use of amoxicillin can lead to an overgrowth of non-susceptible organisms, including fungi and Clostridium difficile. Monitoring is required during prolonged therapy.

• Pregnancy and Breastfeeding: Amoxicillin is generally considered safe for use during pregnancy and breastfeeding, but it should only be used when necessary and as prescribed by a healthcare provider.

Drug Interactions:

• Anticoagulants (e.g., Warfarin): Amoxicillin may enhance the effect of anticoagulants, leading to an increased risk of bleeding. Monitoring of prothrombin time is recommended.

• Methotrexate: Amoxicillin may increase the levels of methotrexate, enhancing its toxic effects.

• Oral Contraceptives: Although not common, antibiotics like amoxicillin can reduce the effectiveness of oral contraceptives, so additional contraceptive measures may be required.

• Allopurinol: The combination of amoxicillin and allopurinol can increase the risk of developing a rash.

Conclusion:

Amoxicillin (Axmel) 125mg/5ml Powder for Suspension is an effective antibiotic for the treatment of a wide range of bacterial infections. It is especially useful for children due to its liquid formulation. Always follow the prescribed dosing instructions and complete the full course of treatment to ensure the best outcomes and minimize the risk of antibiotic resistance. If any serious side effects or allergic reactions occur, seek immediate medical attention.