Betahistine Dihydrochloride (Dizimarc) 8mg Aniti Verttigo Tablet 100's

Certainly! Below is the detailed information for Betahistine Dihydrochloride (Dizimarc) 8mg Anti-Vertigo Tablet 100's:

Product Description:

Betahistine Dihydrochloride (Dizimarc) is a medication commonly used to treat vertigo and dizziness associated with Meniere’s disease and other vestibular disorders. Betahistine works by improving blood flow to the inner ear, which helps to reduce the pressure inside the ear and improve balance. It is particularly effective in reducing the frequency and severity of vertigo attacks, as well as other symptoms like tinnitus (ringing in the ears) and hearing loss associated with inner ear disorders.

Dizimarc comes in 8mg tablets, and each bottle contains 100 tablets.

Indications:

Betahistine Dihydrochloride (Dizimarc) is primarily indicated for the following:

1. Meniere's Disease:

   • Used to treat the vertigo symptoms associated with Meniere’s disease, a condition affecting the inner ear that causes dizziness, ringing in the ears (tinnitus), and hearing loss.

2. Vertigo and Balance Disorders:

   • Betahistine is used to alleviate vertigo and dizziness caused by various vestibular (inner ear) disorders. This includes conditions that disrupt the balance system, leading to symptoms of dizziness, imbalance, and nausea.

3. Vestibular Dysfunction:

   • It is used for the management of vestibular dysfunction resulting in dizziness or a sensation of spinning (vertigo).

Dosage:

The dosing of Betahistine Dihydrochloride (Dizimarc) is generally individualized, depending on the severity of symptoms and the patient's response to the medication:

• Initial Dose:

  • The usual starting dose is 1 tablet (8mg) taken three times daily.

• Maintenance Dose:

  • The dose may be adjusted by your doctor depending on the patient’s response to treatment. Some patients may be increased to 16mg or 24mg per day (up to 3 tablets of 8mg per day), taken in divided doses.

• Maximum Dose:

  • The maximum recommended dose is 48mg per day, which typically consists of 3 tablets of 8mg taken daily (in divided doses).

• Administration:

  • Betahistine should be taken with food to minimize gastrointestinal upset.

  • The tablets should be swallowed whole with water. Do not chew or crush the tablet.

Side Effects:

While Betahistine Dihydrochloride (Dizimarc) is generally well-tolerated, there are some potential side effects. Common and serious side effects include:

Common Side Effects:

• Headache.

• Nausea.

• Indigestion or stomach discomfort.

• Dizziness or feeling lightheaded, especially when standing up too quickly (orthostatic hypotension).

• Flushing or warmth.

Serious Side Effects:

• Allergic reactions: This may include rash, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing.

• Severe stomach pain or ulceration: Could indicate an underlying gastric ulcer or inflammation.

• Unusual bleeding or bruising: Could be a sign of blood disorders.

If any of these serious side effects occur, immediate medical attention should be sought.

Contraindications:

Betahistine Dihydrochloride (Dizimarc) is contraindicated in the following conditions:

1. Hypersensitivity to Betahistine:

   • Betahistine is contraindicated in individuals with a known allergy to Betahistine or any of the tablet's components.

2. Pheochromocytoma:

   • Betahistine should not be used in patients with pheochromocytoma, a rare tumor of the adrenal glands, as it may trigger an increase in blood pressure due to the release of catecholamines (adrenaline).

3. Peptic Ulcers or Gastric Disorders:

   • Betahistine should be avoided in patients with a history of gastric ulcers or severe gastrointestinal disorders, as it may cause gastric irritation or worsen existing conditions.

4. Pregnancy:

   • Betahistine is not recommended during pregnancy, as its safety in pregnant women has not been well-established. If pregnancy occurs while taking Betahistine, consult your healthcare provider immediately.

5. Breastfeeding:

   • It is unclear if Betahistine passes into breast milk, so it should be used with caution during breastfeeding. Consult your healthcare provider if you are breastfeeding or planning to breastfeed.

Precautions:

• Liver Disease: Patients with impaired liver function should use Betahistine with caution and should be monitored for any signs of liver damage during treatment.

• Kidney Disease: If you have renal impairment, the use of Betahistine should be carefully monitored.

• Gastric Disorders: Patients with gastric ulcers, gastritis, or a history of gastrointestinal issues should use Betahistine cautiously as it can cause stomach irritation.

• Driving and Operating Machinery: Betahistine may cause dizziness or lightheadedness, so patients should be cautious when driving or operating heavy machinery until they know how the medication affects them.

• Elderly Patients: Older adults may be more sensitive to the effects of Betahistine, particularly dizziness. Caution should be exercised in prescribing Betahistine to elderly patients.

Drug Interactions:

Betahistine can interact with certain medications, including:

• Antihistamines: Since Betahistine is a histamine analogue, taking it with other antihistamines (e.g., diphenhydramine) may reduce its effectiveness.

• Monoamine Oxidase Inhibitors (MAOIs): Taking MAOIs with Betahistine may cause an increase in blood pressure due to an enhanced release of catecholamines, which is particularly concerning for patients with pheochromocytoma.

• Corticosteroids: Using Betahistine with corticosteroids (e.g., prednisone) may increase the risk of gastric irritation and ulcers.

Always inform your doctor or pharmacist about all other medications you are taking, including over-the-counter drugs, vitamins, and supplements, to avoid any potentially harmful interactions.

Summary:

Betahistine Dihydrochloride (Dizimarc) is an antivertigo medication used to treat Meniere’s disease, vestibular disorders, and balance issues by improving blood flow to the inner ear and regulating pressure. The usual dose is 8mg taken three times daily, with the dose adjusted according to individual response. The maximum daily dose is 48mg (3 tablets of 8mg).

Common side effects include headache, nausea, and gastric discomfort, while more serious side effects could involve gastric ulcers, allergic reactions, and unusual bleeding. Betahistine is contraindicated in individuals with pheochromocytoma, gastric ulcers, or those who are pregnant or breastfeeding.

As always, consult a healthcare provider before starting treatment with Betahistine to ensure it is safe and appropriate for your medical condition.