Candesartan (Giran 8) 8mg Angiotensin 2 Receptor Blocker Tablet 30's

Certainly! Here’s the detailed information for Candesartan (Giran 8) 8mg Angiotensin 2 Receptor Blocker Tablet 30's:

Product Description:

Candesartan (Giran 8) 8mg Angiotensin 2 Receptor Blocker Tablet is a medication used to treat high blood pressure (hypertension) and heart failure. The active ingredient, Candesartan, belongs to the class of Angiotensin II Receptor Blockers (ARBs). Candesartan works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby helping to relax the blood vessels and lower blood pressure. This makes it useful for treating hypertension and improving heart function in heart failure. This formulation contains 8mg of Candesartan per tablet, and it is typically packaged in a 30-tablet bottle.

Indications:

Candesartan (Giran 8) is indicated for the following conditions:

• Hypertension (High Blood Pressure): Candesartan is used to lower high blood pressure, reducing the risk of complications such as stroke, heart attack, and kidney damage.

• Heart Failure: Candesartan is used in the management of heart failure to improve heart function, reduce symptoms, and lower the risk of hospitalization and death from heart failure.

• Chronic Kidney Disease (in certain patients): Candesartan may be used to protect kidney function in patients with kidney disease, particularly those who also have high blood pressure or diabetes.

Dosage:

The dosage of Candesartan (Giran 8) will depend on the patient’s medical condition and how well they respond to the medication. The typical dosages are:

• For Hypertension (High Blood Pressure):

  • Initial Dose: Typically, 8mg once daily.

  • Maintenance Dose: The dose may be increased to 16mg once daily if needed, up to a maximum dose of 32mg once daily, depending on the patient’s blood pressure response.

• For Heart Failure:

  • Initial Dose: Typically, 4mg to 8mg once daily.

  • Maintenance Dose: The dose can be increased to 16mg to 32mg once daily, depending on the patient’s tolerance and clinical condition.

Important Notes:

• The dose may be adjusted based on the patient’s condition, age, kidney function, and other factors.

• Candesartan can be taken with or without food, usually once a day.

• It is essential to follow your healthcare provider’s instructions and adjust doses based on medical advice.

Side Effects:

Common side effects of Candesartan (Giran 8) include:

• Dizziness or lightheadedness: Particularly when standing up quickly due to a drop in blood pressure.

• Headache: A common side effect, especially when starting treatment or adjusting the dose.

• Fatigue: Some individuals may feel unusually tired or weak.

• Upper respiratory tract infections: Symptoms like sore throat, nasal congestion, or cough can occur.

• Back pain or muscle pain: Some people may experience mild musculoskeletal discomfort.

Serious but less common side effects include:

• Hypotension (low blood pressure): This can cause dizziness, fainting, or a feeling of lightheadedness, especially after the first dose.

• Hyperkalemia (high potassium levels): This can lead to symptoms like weakness, fatigue, irregular heartbeat, and numbness.

• Kidney Dysfunction: Rarely, Candesartan can impair kidney function, which may show as elevated levels of creatinine or blood urea nitrogen (BUN).

• Angioedema (swelling of the face, lips, or throat): This is a serious reaction that requires immediate medical attention.

• Liver-related issues: In rare cases, liver problems may occur, causing jaundice or dark urine.

Contraindications:

Candesartan (Giran 8) should not be used in the following conditions:

• Hypersensitivity to Candesartan or any component of the tablet: If you have an allergy or hypersensitivity to Candesartan or any of its ingredients, you should not take this medication.

• Pregnancy: Candesartan is contraindicated during pregnancy, particularly during the second and third trimesters, as it can cause fetal harm, including birth defects or death. It is important to stop using this medication if pregnancy is detected.

• Breastfeeding: Candesartan should not be used while breastfeeding, as it may pass into breast milk and harm the baby.

• Severe Renal Impairment: Candesartan should not be used in patients with severe kidney dysfunction, particularly in those with bilateral renal artery stenosis or other serious kidney problems.

• Bilateral Renal Artery Stenosis: Candesartan is contraindicated in patients with narrowing of both kidneys' arteries, as it can cause a significant decline in kidney function.

• Hyperkalemia (High Potassium Levels): Candesartan should not be used if the patient has elevated potassium levels in the blood.

Precautions:

• Renal Impairment: Candesartan should be used with caution in patients with mild to moderate kidney disease. Monitoring kidney function during treatment is recommended.

• Electrolyte Imbalances: Candesartan can affect potassium levels, leading to hyperkalemia. Patients should have their potassium levels monitored regularly, especially if they are taking potassium supplements or potassium-sparing diuretics.

• Hypotension (Low Blood Pressure): When initiating treatment or increasing the dose, blood pressure should be monitored. Patients may experience dizziness or lightheadedness due to the blood pressure-lowering effect of the medication.

• Liver Impairment: Use Candesartan with caution in patients with liver disease, as dosage adjustments may be required.

• Concomitant Use with Other Antihypertensive Agents: Combining Candesartan with other antihypertensive drugs (such as ACE inhibitors, diuretics) may enhance the blood pressure-lowering effect. Blood pressure should be monitored to avoid excessive hypotension.

Drug Interactions:

• Potassium-Sparing Diuretics and Potassium Supplements: Concomitant use can increase the risk of hyperkalemia (high potassium levels).

• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs may reduce the blood pressure-lowering effect of Candesartan and can increase the risk of kidney problems when taken together.

• ACE Inhibitors: When combined with ACE inhibitors, particularly in patients with kidney disease or diabetes, there is an increased risk of renal impairment and hyperkalemia.

• Lithium: Candesartan can increase the serum concentration of lithium, leading to potential toxicity. Lithium levels should be closely monitored.

Summary:

Candesartan (Giran 8) is an Angiotensin II Receptor Blocker (ARB) used to treat hypertension and heart failure. By blocking the action of angiotensin II, it helps lower blood pressure and improves heart function. The 8mg tablet is typically taken once daily, with dosage adjustments based on the patient’s medical condition and response. Like all medications, Candesartan may cause side effects such as dizziness, headache, and hyperkalemia, and it should be used with caution in patients with kidney or liver issues. Always follow your healthcare provider’s instructions for safe use and dosage adjustments.

For more personalized advice, it’s important to consult with a healthcare provider.