Cefixime (Tocef) 20mg/ml Granules For Suspension Oral Drops 10ml

Antibacterial
(CEPHALOSPORIN)

Certainly! Here's a detailed breakdown for Cefixime (Tocef) 20mg/ml Granules For Suspension Oral Drops 10ml:

Product Description:

Cefixime (Tocef) 20mg/ml Granules For Suspension Oral Drops 10ml is an antibiotic suspension in drop form, primarily used for treating bacterial infections. It contains Cefixime, a third-generation cephalosporin, as its active ingredient. Each milliliter of the suspension contains 20 mg of Cefixime. The drops are provided as a granule powder that must be reconstituted with water before use. The 10ml bottle provides a convenient dose for children or individuals who have difficulty swallowing tablets or larger volumes of liquid.

Cefixime works by inhibiting bacterial cell wall synthesis, ultimately killing or inhibiting the growth of a wide variety of susceptible bacteria.

Indications:

Cefixime (Tocef) 20mg/ml Granules for Suspension Oral Drops are indicated for the treatment of various bacterial infections, including:

1. Upper Respiratory Tract Infections:

   • Pharyngitis (sore throat)

   • Tonsillitis

   • Sinusitis

2. Lower Respiratory Tract Infections:

   • Bronchitis

   • Pneumonia

3. Urinary Tract Infections (UTIs):

   • Cystitis (bladder infection)

   • Pyelonephritis (kidney infection)

4. Ear Infections (Otitis Media):

   • Common in children

5. Gonorrhea (a sexually transmitted infection caused by Neisseria gonorrhoeae)

6. Other bacterial infections: Such as soft tissue infections, some gastrointestinal infections, etc.

Note: Cefixime is effective only against bacterial infections and will not work against viral infections like the common cold or flu.

Dosages:

The dosage of Cefixime (Tocef) 20mg/ml Oral Drops depends on the patient's age, the type of infection, and the severity of the infection.

For Children:

• Children aged 6 months to 12 years:

  • The general dose is typically 8 mg/kg/day, given once daily or divided into two doses (depending on the healthcare provider’s instructions).

  • For example, for a child weighing 10 kg (about 22 lbs), the daily dose would be 80 mg.

  • The liquid form allows for easy administration based on the child's weight.

• For Gonorrhea (in adults and children over 12 years):

  • Single dose of 400 mg is given as a one-time dose.

For Adults:

• Adults and children over 12 years: The dose is typically 200 mg to 400 mg daily, either as a single dose or divided into two doses.

Important: Always follow the exact dosing instructions provided by your doctor or pharmacist, and ensure the suspension is well-mixed before each use.

Side Effects:

While Cefixime (Tocef) is generally well tolerated, like all medications, it can cause side effects. The common and serious side effects include:

Common Side Effects:

• Gastrointestinal issues:

  • Diarrhea

  • Nausea

  • Vomiting

  • Abdominal pain

  • Indigestion

• Headache

• Dizziness or lightheadedness

• Rash or mild skin reactions

Serious Side Effects (Rare):

• Severe allergic reactions (anaphylaxis), including swelling of the face, lips, tongue, or throat, difficulty breathing, or chest tightness.

• Clostridium difficile-associated diarrhea (CDAD), which can result in severe watery diarrhea, abdominal cramping, and fever.

• Liver problems: Symptoms may include jaundice (yellowing of the skin or eyes), dark urine, or unusual fatigue.

• Kidney problems: Changes in urination or swelling in the legs or ankles.

• Blood disorders: Such as low levels of red or white blood cells, or platelets, which may cause unusual bruising or bleeding.

• Severe skin reactions: Blistering, peeling, or rashes that may indicate more severe complications.

If any of these serious side effects occur, medical attention should be sought immediately.

Contraindications:

Cefixime (Tocef) 20mg/ml Granules for Suspension should not be used in the following situations:

1. Hypersensitivity (allergic reaction) to Cefixime or any other cephalosporin antibiotics.

2. Severe allergic reaction to penicillin: Because there is a cross-sensitivity between cephalosporins and penicillins, individuals with a history of severe allergic reactions (e.g., anaphylaxis) to penicillin may be at risk when using Cefixime.

3. History of gastrointestinal conditions, such as severe colitis (inflammation of the colon), especially if caused by previous antibiotic use.

4. Severe renal (kidney) impairment: Cefixime should be used with caution in individuals with kidney problems. Dosage adjustments may be needed.

5. Phenylketonuria (PKU): The product may contain phenylalanine, so it should be used cautiously in patients with PKU.

Precautions:

• Pregnancy: While Cefixime is categorized as pregnancy category B (suggesting it is generally considered safe), it should only be used during pregnancy if the benefits outweigh the potential risks. Consult a healthcare provider before use.

• Breastfeeding: Cefixime passes into breast milk in small amounts, so consult a doctor before using it while breastfeeding.

• Diarrhea: Antibiotics like Cefixime can cause an overgrowth of Clostridium difficile in the intestines, leading to severe diarrhea. If diarrhea occurs during or after the course of treatment, seek medical advice immediately.

• Renal (Kidney) Impairment: Dose adjustments may be necessary for patients with kidney dysfunction, as Cefixime is excreted through the kidneys.

Important Note: Always complete the prescribed course of antibiotics as directed by your healthcare provider, even if you start feeling better before finishing the medication, to ensure the infection is fully treated and to help prevent antibiotic resistance.