Ciprofloxacin (Ciprosan) 500mg Tablet 100's

Product Description:

Ciprofloxacin (Ciprosan) 500mg Tablets are a fluoroquinolone antibiotic used to treat a variety of bacterial infections. Ciprofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are enzymes essential for bacterial DNA replication, transcription, and repair. This prevents bacteria from multiplying and spreading, effectively treating infections caused by susceptible bacteria.

Each tablet contains 500mg of Ciprofloxacin and is designed for oral administration. Available in 100 tablets per pack, this medication is commonly prescribed for both acute and chronic bacterial infections.

Key Features:

• Active Ingredient: Ciprofloxacin 500mg per tablet.

• Formulation: Tablet for oral use.

• Mechanism of Action: Inhibits bacterial DNA synthesis by targeting DNA gyrase and topoisomerase IV.

• Indications: Used to treat a wide range of bacterial infections.

• Packaging: Available in 100 tablets per pack.

Indications:

Ciprofloxacin (Ciprosan) 500mg tablets are indicated for the treatment of the following bacterial infections:

1. Respiratory Tract Infections:

   • Pneumonia.

   • Bronchitis (acute and chronic).

   • Sinusitis.

2. Urinary Tract Infections (UTIs):

   • Cystitis (bladder infections).

   • Pyelonephritis (kidney infections).

   • Complicated UTIs.

3. Gastrointestinal Infections:

   • Traveler’s diarrhea.

   • Infections caused by Salmonella, Shigella, E. coli.

   • Enteric fever (typhoid fever).

4. Skin and Soft Tissue Infections:

   • Cellulitis.

   • Wound infections.

   • Abscesses.

5. Bone and Joint Infections:

   • Osteomyelitis.

6. Eye Infections:

   • Conjunctivitis (eye infection).

7. Sexually Transmitted Infections:

   • Gonorrhea.

8. Anthrax:

   • Post-exposure prophylaxis for anthrax.

Dosage:

The dosage of Ciprofloxacin (Ciprosan) 500mg tablets varies based on the type and severity of the infection. The following are general guidelines:

• Adults:

  • For mild to moderate infections: Take 1 tablet (500mg) twice daily.

  • For severe infections: The dose may be increased to 750mg twice daily depending on the infection and doctor's recommendation.

• Duration:

  • Typically, treatment lasts for 7-14 days, depending on the infection. Always complete the full course of antibiotics even if symptoms improve.

• Children (For approved uses only):

  • The dose for children is typically based on weight and severity of infection. However, Ciprofloxacin is generally not recommended for children unless necessary due to potential effects on developing joints and cartilage.

Administration:

• Take the tablet with a full glass of water.

• Can be taken with or without food. However, taking it with food may help reduce stomach upset.

• Do not chew, crush, or split the tablet. Swallow it whole.

• Take at regular intervals to maintain consistent levels of the medication in your bloodstream.

Side Effects:

Like all medications, Ciprofloxacin (Ciprosan) 500mg tablets may cause side effects, although not everyone experiences them. Some common side effects include:

• Gastrointestinal issues:

  • Nausea, vomiting, diarrhea, stomach pain.

• Headache and dizziness.

• Rash or itching.

More serious side effects (though rare) include:

• Tendon problems: Tendonitis or tendon rupture, especially in older adults or those taking corticosteroids.

• Severe allergic reactions: Swelling of the face, throat, and lips, and difficulty breathing.

• Liver damage: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, and stomach pain.

• Severe diarrhea (Clostridium difficile infection).

• CNS effects: Confusion, hallucinations, seizures, or tremors (especially in elderly patients).

• Cardiovascular effects: QT prolongation (which may lead to abnormal heart rhythms).

If you experience any of these serious side effects, contact your healthcare provider immediately.

Contraindications:

Ciprofloxacin (Ciprosan) 500mg tablets should not be used in the following conditions:

1. Hypersensitivity (allergic reaction) to Ciprofloxacin or any other fluoroquinolone antibiotic.

2. Tendon disorders: Ciprofloxacin should not be used in patients with a history of tendonitis or tendon rupture, especially those who are taking corticosteroids.

3. Pregnancy: Ciprofloxacin should be avoided during pregnancy unless absolutely necessary.

4. Breastfeeding: Ciprofloxacin is excreted in breast milk, so it should be avoided during breastfeeding unless prescribed by a healthcare provider.

5. Children under 18 years (except in specific situations): Ciprofloxacin may affect cartilage and bone growth in young children.

Warnings and Precautions:

• Severe Allergic Reactions: Anaphylaxis and other severe allergic reactions have been reported. Seek immediate medical help if you experience symptoms such as difficulty breathing, rash, or swelling.

• Tendonitis and Tendon Rupture: Fluoroquinolones like Ciprofloxacin have been associated with an increased risk of tendonitis and tendon rupture, especially in the elderly and those on corticosteroids. Discontinue treatment at the first sign of tendon pain, swelling, or inflammation.

• CNS Effects: Ciprofloxacin may cause CNS effects such as dizziness, confusion, or seizures, especially in elderly patients or those with existing neurological conditions.

• QT Prolongation: Ciprofloxacin may cause QT interval prolongation, which can lead to abnormal heart rhythms. Use caution in patients with a history of arrhythmias or those on medications that prolong the QT interval.

• Liver Function: Monitor liver function during long-term therapy or in patients with existing liver disease.

• Diarrhea: Ciprofloxacin may cause severe diarrhea due to Clostridium difficile infection. If diarrhea is severe, stop the medication and seek medical advice.

Drug Interactions:

Ciprofloxacin (Ciprosan) 500mg may interact with several other medications, including:

• Antacids, iron supplements, zinc, or multivitamins: These can reduce the absorption of Ciprofloxacin. It should be taken at least 2 hours before or 6 hours after these medications.

• Warfarin: Ciprofloxacin may increase the effects of Warfarin, leading to a higher risk of bleeding. Monitoring of INR levels is recommended.

• Corticosteroids: Concurrent use with corticosteroids increases the risk of tendonitis and tendon rupture.

• Theophylline: Ciprofloxacin may increase the levels of Theophylline in the blood, potentially leading to toxicity.

• Probenecid: May decrease the excretion of Ciprofloxacin, increasing its levels in the blood.

• Antiarrhythmics: Ciprofloxacin may increase the risk of QT prolongation when taken with drugs that affect heart rhythm.

Storage:

• Store Ciprofloxacin (Ciprosan) tablets at room temperature (15°C to 30°C).

• Keep in a dry place, away from moisture and heat.

• Keep out of reach of children.

Conclusion:

Ciprofloxacin (Ciprosan) 500mg tablets are an effective antibiotic used to treat a wide range of bacterial infections. It works by inhibiting bacterial DNA synthesis, making it useful for treating conditions like respiratory infections, urinary tract infections, gastrointestinal infections, and skin infections. However, it should be used with caution in certain populations, such as the elderly or patients with a history of tendonitis, heart problems, or neurological disorders. Always follow the prescribed dosage and complete the full course of treatment to prevent antibiotic resistance. If you experience any severe side effects or allergic reactions, seek medical attention immediately.