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Bambang Pharmaceutical Depot Inc.

Co Amoxiclav (Clovimed) 156.25mg per 5 ml Powder for Suspension 60ml

Co Amoxiclav (Clovimed) 156.25mg per 5 ml Powder for Suspension 60ml

Regular price ₱176.00
Regular price ₱352.00 Sale price ₱176.00
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Co Amoxiclav (Clovimed) 156.25mg per 5 ml Powder for Suspension 60ml

Product Description:

Co Amoxiclav (Clovimed) is a combination of Amoxicillin and Clavulanic acid in the form of a powder for oral suspension. It is an antibiotic used to treat a variety of bacterial infections caused by susceptible organisms. The Amoxicillin component is a broad-spectrum penicillin-type antibiotic, while Clavulanic acid is a beta-lactamase inhibitor that helps prevent certain bacteria from inactivating the amoxicillin.

  • Each 5 ml of prepared suspension contains:

    • Amoxicillin 125mg

    • Clavulanic acid 31.25mg

The product comes as a 60ml bottle of powder that must be reconstituted with water to create an oral suspension. Once reconstituted, it provides a liquid formulation that is easier to administer, especially for children or patients who have difficulty swallowing tablets.


Indications:

Co Amoxiclav (Clovimed) is prescribed to treat a variety of bacterial infections, including those caused by penicillin-sensitive organisms. Some common indications include:

  1. Respiratory Tract Infections:

    • Pneumonia

    • Bronchitis

    • Sinusitis

    • Pharyngitis (sore throat)

    • Tonsillitis

  2. Urinary Tract Infections:

    • Cystitis

    • Pyelonephritis (kidney infections)

  3. Skin and Soft Tissue Infections:

    • Abscesses

    • Cellulitis

    • Wound infections

    • Impetigo

  4. Ear Infections:

    • Otitis media (middle ear infections)

  5. Dental Infections:

    • Dental abscesses

  6. Other Infections:

    • Bone and joint infections

    • Intra-abdominal infections


Dosages:

The dosage of Co Amoxiclav (Clovimed) will depend on the patient's age, the severity of the infection, and other individual factors. The usual recommended dosages are as follows:

  • Adults and Children over 12 years:

    • The usual dose is 10ml of the suspension (equivalent to 250mg Amoxicillin + 62.5mg Clavulanic acid) every 8 hours.

    • For more severe infections, the dose may be increased to 15ml (equivalent to 375mg Amoxicillin + 93.75mg Clavulanic acid) every 8 hours.

  • Children (under 12 years):

    • Children aged 6-12 years: 5-10ml (equivalent to 125mg-250mg Amoxicillin + 31.25mg-62.5mg Clavulanic acid) every 8 hours.

    • Children aged 2-6 years: 2.5-5ml (equivalent to 62.5mg-125mg Amoxicillin + 15.625mg-31.25mg Clavulanic acid) every 8 hours.

    • Children under 2 years: Consult your healthcare provider for the exact dosage based on weight and the severity of the infection.

  • For severe infections or severe kidney conditions, the dosage may be adjusted by the prescribing physician.

Preparation of Suspension:

  1. Add the required amount of water (as per the instructions on the bottle).

  2. Shake the bottle well to ensure the powder is fully dissolved and the suspension is homogeneous.

  3. The prepared suspension should be stored in the refrigerator and used within 7 days of reconstitution. Shake well before each dose.


Side Effects:

Common side effects may include:

  1. Gastrointestinal Symptoms:

    • Diarrhea

    • Nausea

    • Vomiting

    • Abdominal pain

  2. Skin Reactions:

    • Rash

    • Itching

    • Urticaria (hives)

  3. Liver Effects:

    • Elevated liver enzymes (transaminases)

    • Jaundice (yellowing of the skin or eyes) in rare cases

  4. Hematological Effects:

    • Eosinophilia (elevated eosinophil count)

    • Thrombocytopenia (low platelet count)

    • Leukopenia (low white blood cell count)

  5. Hypersensitivity Reactions:

    • Anaphylaxis (severe allergic reaction)

    • Angioedema (swelling of the face, lips, or throat)

  6. Other Effects:

    • Headache

    • Dizziness

    • Fatigue


Contraindications:

  1. Hypersensitivity to Penicillins or Cephalosporins:

    • Do not use if you have a history of allergic reactions to penicillin, cephalosporins, or any other components of the formulation.

  2. Liver Dysfunction:

    • Avoid use in patients with a history of severe liver disease or jaundice caused by previous use of Amoxicillin-Clavulanate.

  3. Mononucleosis (Mono):

    • Caution should be exercised when prescribing Co Amoxiclav to individuals with mononucleosis, as they are more likely to develop a rash.

  4. Renal Impairment:

    • Use with caution in patients with severe kidney dysfunction, as they may require dose adjustments.

  5. Pregnancy and Breastfeeding:

    • Pregnancy Category B: Co Amoxiclav is generally considered safe during pregnancy, but should only be used when necessary. Always consult with your healthcare provider before using this medication during pregnancy.

    • Breastfeeding: Small amounts of Amoxicillin and Clavulanic acid are excreted in breast milk. While considered safe, consult with your healthcare provider before taking Co Amoxiclav while breastfeeding.


Precautions:

  1. Prolonged Use:

    • Prolonged use of Co Amoxiclav may lead to superinfections with organisms not susceptible to the medication.

  2. Clostridium difficile-associated Diarrhea (CDAD):

    • Antibiotics, including Co Amoxiclav, may alter normal gut flora and lead to Clostridium difficile-associated diarrhea. Severe cases may require discontinuation of the antibiotic and appropriate treatment.

  3. Allergic Reactions:

    • Use with caution in patients with a history of allergic reactions to antibiotics or other medications. Immediate medical attention is needed in case of any anaphylactic reactions.

  4. Renal and Hepatic Monitoring:

    • Regular monitoring of renal and hepatic function may be necessary, especially in patients with pre-existing conditions affecting these organs.


Conclusion:

Co Amoxiclav (Clovimed) is a widely used antibiotic for treating a broad spectrum of bacterial infections. It is a combination of Amoxicillin and Clavulanic acid, which enhances its effectiveness against beta-lactamase-producing bacteria. While generally safe, it may cause side effects like gastrointestinal disturbances or allergic reactions, and should be avoided in patients with certain conditions like liver disease or severe hypersensitivity to penicillin. Always follow the prescribed dosage and consult a healthcare professional for any concerns regarding its use.

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