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Bambang Pharmaceutical Depot Inc.

Dextrose in Lactated Ringers Solution (Nir D5LR Blue) (Sajar) 5% Solution for I.V Infusion 1000ml

Dextrose in Lactated Ringers Solution (Nir D5LR Blue) (Sajar) 5% Solution for I.V Infusion 1000ml

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Here’s a detailed overview of Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) (Sajar) 5% Solution for I.V. Infusion 1000ml:

Product Description:

Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) (Sajar) is a sterile intravenous (IV) solution used to provide hydration, replenish electrolytes, and supply energy in the form of dextrose (glucose) to patients who are unable to take fluids or nutrition orally. The solution consists of 5% dextrose (glucose) dissolved in Lactated Ringer’s Solution, a commonly used electrolyte solution that contains sodium chloride (NaCl), potassium chloride (KCl), calcium chloride (CaCl2), and lactate.

The 1000 ml container is designed for infusion into the bloodstream, typically in a medical setting, such as hospitals or clinics, to treat conditions that require fluid and electrolyte replacement or to provide calories in patients who are fasting, dehydrated, or undergoing medical procedures.

The blue labeling and packaging (such as “Blue” in the name) typically indicate specific branding or a distinct line of intravenous solutions from the manufacturer, which may help in easy identification.

Indications:

Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) is primarily used for:

  1. Fluid and Electrolyte Replenishment: Used in patients who require fluid resuscitation or are experiencing dehydration due to illness, surgery, or trauma.

  2. Hypoglycemia: For patients with low blood sugar (hypoglycemia), the dextrose in the solution provides an immediate source of glucose to raise blood sugar levels.

  3. Intravenous Nutrition: In patients who are unable to eat or drink, this solution provides both hydration and energy in the form of glucose, which can be absorbed into the bloodstream.

  4. Surgical and Post-operative Recovery: Often used in perioperative settings to maintain fluid balance, provide energy, and support electrolyte levels during and after surgery.

  5. Lactate Metabolism Disorders: The lactate component can be metabolized in the liver and may help correct acidosis, which is common in conditions such as shock or severe dehydration.

  6. Burns and Trauma: In patients with severe burns, trauma, or other conditions causing fluid loss, this solution is used for hydration and replenishing electrolytes.

Dosages (Usage Instructions):

Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) should only be administered by healthcare professionals in a medical setting, and the dosage will vary depending on the patient's condition, weight, and clinical status. However, general guidelines include:

  • Typical Dosage: The usual infusion rate for adult patients can range from 50 to 100 ml per hour depending on the severity of the patient’s dehydration, fluid requirements, and glucose needs.

  • Administration: The solution is typically administered via intravenous infusion into the patient's vein through an IV drip or IV catheter. The healthcare provider will monitor the patient closely during the infusion to ensure appropriate fluid balance and correct glucose levels.

  • Dosage Adjustments:

    • In patients with diabetes or impaired glucose tolerance, the glucose level and infusion rate must be carefully adjusted to avoid hyperglycemia (high blood sugar).

    • In pediatric patients, the dose and rate of infusion are adjusted based on age, weight, and clinical condition.

  • Duration of Infusion: The infusion rate and duration should be tailored to the patient's clinical needs. Infusion rates and amounts may differ for adult, pediatric, or geriatric patients based on their overall health status and specific requirements.

Side Effects:

While Dextrose in Lactated Ringer's Solution is generally well tolerated, some potential side effects include:

  • Hyperglycemia: The dextrose (glucose) content can lead to high blood sugar levels, especially in patients with diabetes or those receiving large amounts of the solution.

  • Fluid Overload: Excessive infusion of the solution can lead to fluid overload, especially in patients with heart failure or kidney issues, potentially causing edema, swelling, or shortness of breath.

  • Electrolyte Imbalance: The solution contains electrolytes, and improper administration or imbalances in the patient’s condition can lead to hyperkalemia (high potassium levels), hypernatremia (high sodium levels), or other electrolyte disturbances.

  • Infection at Infusion Site: Any intravenous solution can cause local infection or irritation at the site of infusion, including pain, swelling, or redness at the IV site.

  • Hypotension (Low Blood Pressure): In some cases, particularly if the patient has an existing low blood pressure or is very dehydrated, there may be a risk of hypotension after the infusion.

  • Acidosis: In rare cases, lactic acidosis may occur if there is an issue with lactate metabolism or if the infusion is not monitored properly.

Contraindications:

Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) should not be used in the following situations:

  • Severe Hyperglycemia: Patients with uncontrolled diabetes or hyperglycemia (high blood sugar) should not receive this solution unless closely monitored. It may worsen their condition due to the dextrose (glucose) content.

  • Severe Renal (Kidney) Dysfunction: In patients with severe kidney disease or renal failure, the infusion of this solution may worsen the condition due to the presence of electrolytes and the need for kidney filtration.

  • Congestive Heart Failure (CHF): Patients with heart failure may be at risk for fluid overload, and the solution should be used cautiously, with frequent monitoring.

  • Hyperkalemia or Hypercalcemia: Patients with high potassium levels (hyperkalemia) or high calcium levels (hypercalcemia) should avoid this solution as it contains electrolytes that can worsen these conditions.

  • Lactic Acidosis: The presence of lactate in the solution may exacerbate lactic acidosis in patients who have impaired lactate metabolism, so caution is needed in patients with conditions such as shock, severe liver disease, or respiratory failure.

  • Allergy to Components: Patients with known hypersensitivity or allergy to any of the components of the solution (such as dextrose, sodium chloride, potassium chloride, calcium chloride, or lactate) should not use this product.

Conclusion:

Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) (Sajar) 5% Solution for I.V. Infusion 1000ml is an essential intravenous solution for fluid and electrolyte replacement, providing hydration and energy in the form of glucose for patients unable to take fluids or nutrition orally. It is widely used in medical settings for hydration, hypoglycemia treatment, surgical recovery, and electrolyte imbalance correction.

While the solution is generally safe, healthcare providers must monitor the patient’s blood glucose levels and electrolytes closely during infusion, especially in patients with diabetes, kidney issues, or heart failure. The solution is contraindicated in patients with severe hyperglycemia, renal failure, heart failure, or those who have issues with lactate metabolism.

As with any medical treatment, Dextrose in Lactated Ringer's Solution (Nir D5LR Blue) should only be administered under the supervision of qualified healthcare professionals, ensuring the appropriate infusion rate and careful monitoring of potential side effects.

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