Domperidone Maleate 10mg Tablet 100's

Generic Name: DOMPERIDONE MALEATE

Brand Name: MOTILIA

Strength: 10mg

Form: TABLET

Manufacturer: 2 WORLD LABORATORIES 

Imported and Distributed by: 2 WORLD TRADERS SUBIC, INC.

Classification: GASTROKINETIC/PROKINETICS

Indication/Uses: 

1. Nausea and Vomiting

   • Usage: Domperidone is used to relieve symptoms of nausea and vomiting from various causes, including gastrointestinal disorders, medications, and conditions such as migraine.

2. Gastroparesis

   • Usage: It is effective in the treatment of gastroparesis, a condition where the stomach cannot empty properly. Domperidone helps in enhancing gastric motility, which alleviates symptoms such as bloating, early satiety, and abdominal discomfort.

3. Gastroesophageal Reflux Disease (GERD)

   • Usage: Domperidone is used in managing GERD by increasing the movement of the stomach and intestines, helping to prevent reflux of stomach contents into the esophagus.

4. Dyspepsia (Indigestion)

   • Usage: It is used to treat symptoms of indigestion, such as feeling full, bloating, and belching, especially in functional dyspepsia.

5. Lactation Stimulation

   • Usage: Off-label, domperidone is sometimes used to stimulate lactation in breastfeeding women by increasing prolactin levels.

Mechanism of Action

Domperidone works by blocking dopamine receptors in the gut and chemoreceptor trigger zone in the brain. By antagonizing these receptors, it enhances gastrointestinal motility and accelerates gastric emptying, and has antiemetic (preventing vomiting) properties.