Imported and Distributed by: RAQUEL-ABBAS PHARMACEUTICALS & GEN. MERCHAND DISE & DISTRIBUTED BY: EXA LIFE CARE PHARMA INC.
Classification: DIURETIC (SULFONAMIDE)
Indication/Uses:
Edema Associated with Congestive Heart Failure
Usage: Furosemide is used to reduce edema (fluid buildup) in patients with congestive heart failure. It helps alleviate symptoms such as swelling in the legs and ankles, and difficulty breathing.
Edema Associated with Liver Cirrhosis
Usage: It is prescribed for patients with liver cirrhosis to manage fluid retention and prevent complications such as ascites (fluid accumulation in the abdomen).
Renal Disease-Associated Edema
Usage: Furosemide is used to treat edema associated with renal disease, including nephrotic syndrome and chronic renal failure.
Acute Pulmonary Edema
Usage: In emergency situations, furosemide can be administered to rapidly reduce fluid overload in the lungs, which can be life-threatening.
Hypertension
Usage: Furosemide is sometimes used as an adjunct treatment for hypertension, especially when other diuretics are not sufficient.
Hypercalcemia
Usage: It can be used to manage hypercalcemia (high levels of calcium in the blood) by increasing the excretion of calcium.
Mechanism of Action
Furosemide works by inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the kidneys. This action prevents the reabsorption of sodium and chloride, leading to increased urine production (diuresis). The increased excretion of water, sodium, chloride, potassium, and calcium helps reduce fluid buildup in the body.
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