Gliclazide (Melanov MR 60) 60mg Modified Release Tablet 100's

Certainly! Below is the requested information for Gliclazide (Melanov MR 60) 60mg Modified Release Tablet 100's:

Product Description:

Gliclazide (Melanov MR 60mg Modified Release Tablet) is an oral medication used for the management of type 2 diabetes mellitus. It is classified as a sulfonylurea drug, and it helps control blood sugar levels by stimulating the pancreas to release insulin, thus promoting better glucose utilization in the body.

The modified-release formulation allows for a controlled, prolonged release of the drug over time, which helps in maintaining more stable blood glucose levels throughout the day and minimizing the peaks and troughs associated with immediate-release formulations.

Each tablet contains 60 mg of Gliclazide in a modified-release form. The product comes in a pack of 100 tablets.

Indications:

Gliclazide (Melanov MR 60mg) is indicated for the treatment of type 2 diabetes mellitus in adults:

1. Monotherapy: For patients whose blood sugar levels are inadequately controlled by diet and exercise alone.

2. Combination Therapy: It can be used in combination with other oral antidiabetic agents or insulin when monotherapy is insufficient to achieve optimal blood glucose control.

It is important that patients continue to follow their prescribed diet and exercise plans in conjunction with Gliclazide therapy.

Dosages:

The dosing of Gliclazide (Melanov MR 60mg) depends on individual patient needs and response to treatment. A typical dosing regimen is as follows:

• Initial dose: The usual starting dose is 30 mg to 60 mg once daily with breakfast.

• Maintenance dose: The dose can be increased gradually based on the patient's blood glucose levels, usually up to 120 mg to 180 mg once daily.

• Maximum dose: The recommended maximum dose is 240 mg per day, typically in the form of one or two tablets.

Note: The dose should be titrated based on the patient’s blood glucose levels and under the guidance of a healthcare provider. Regular monitoring of blood glucose is essential for dose adjustment.

Side Effects:

Like all medications, Gliclazide (Melanov MR 60mg) may cause side effects. Some common and serious side effects include:

1. Common side effects:

   • Hypoglycemia (low blood sugar): Symptoms may include shaking, sweating, dizziness, confusion, and irritability.

   • Nausea or vomiting

   • Headache

   • Weight gain

   • Abdominal discomfort

   • Diarrhea or constipation

2. Serious side effects:

   • Severe hypoglycemia: This can be life-threatening and may require immediate treatment with glucose or glucagon.

   • Allergic reactions: Rash, itching, or swelling, particularly in the face or throat.

   • Hepatic issues: Rare cases of liver dysfunction or jaundice.

   • Blood disorders: Rare instances of thrombocytopenia, leukopenia, or anemia.

   • Pancreatitis: In rare cases, patients may experience inflammation of the pancreas.

Contraindications:

Gliclazide (Melanov MR 60mg) is contraindicated in the following conditions:

1. Hypersensitivity: If you are allergic to gliclazide, other sulfonylureas, or any components of the tablet.

2. Type 1 diabetes: Gliclazide is not suitable for type 1 diabetes as it requires insulin therapy.

3. Severe liver or kidney impairment: It is contraindicated in patients with severe liver or kidney dysfunction, as this can lead to accumulation of the drug in the body and increase the risk of hypoglycemia.

4. Diabetic ketoacidosis: This is a serious complication of diabetes requiring immediate treatment, and Gliclazide should not be used in such cases.

5. Pregnancy and breastfeeding: Gliclazide should not be used during pregnancy or while breastfeeding unless specifically prescribed by a healthcare provider.

Warnings and Precautions:

• Hypoglycemia Risk: Gliclazide can cause hypoglycemia, especially if a dose is missed, meals are skipped, or there is a change in physical activity. Symptoms of hypoglycemia should be promptly treated with glucose.

• Monitoring: Regular monitoring of blood glucose and kidney function is important during treatment with Gliclazide.

• Alcohol: Alcohol can increase the risk of hypoglycemia, so it should be consumed with caution.

• Pregnancy and breastfeeding: If you are pregnant or planning to become pregnant, or if you are breastfeeding, consult your doctor before starting Gliclazide. Insulin may be preferred during pregnancy.

• Other Medications: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements, as they can interact with Gliclazide, either increasing or decreasing its effectiveness.

Storage:

• Store Gliclazide (Melanov MR 60mg) tablets in a cool, dry place, away from direct light.

• Keep the medication out of reach of children.

• Do not use the medication after the expiration date printed on the packaging.

It is important to follow the prescribed treatment plan and consult a healthcare provider regularly for monitoring and adjustments. Always take medications exactly as prescribed and never adjust your dose without consulting your doctor.