Glimepiride 2mg Tablet 100's

Generic Name: GLIMEPIRIDE

Brand Name: GLIMESAPH T2

Strength: 2mg

Form: TABLET

Manufacturer:  SAPPHIRE LIFESCIENCES PVT. LTD.

Imported and Distributed by: NELPA LIFESCIENCES, INC.

Classification: ORAL HYPOGLYCEMIC

Indication/Uses: 

1. Type 2 Diabetes Mellitus:
   • Primary Use: Glimepiride is used to lower blood sugar levels in patients with type 2 diabetes.
   • Monotherapy: Can be used alone when diet and exercise are insufficient for glycemic control.
   • Combination Therapy: Often used in combination with other antidiabetic medications, such as metformin or insulin, to achieve better blood sugar control.

Mechanism of Action:

• Glimepiride belongs to a class of drugs called sulfonylureas. It works by stimulating the release of insulin from the beta cells of the pancreas. This helps lower blood sugar levels by increasing insulin levels in the blood, which allows the body to use glucose more effectively.

Dosage and Administration:

• Dosage:
  • The typical starting dose is 1-2 mg once daily.
  • The dose can be adjusted based on the patient’s blood glucose levels, up to a maximum of 8 mg once daily.
• Administration:
  • Glimepiride is usually taken with breakfast or the first main meal of the day.
  • It should be swallowed whole with water and not chewed or crushed.

Side Effects:

• Common Side Effects:
  • Hypoglycemia (low blood sugar)
  • Nausea
  • Dizziness
  • Headache
  • Weight gain
• Serious Side Effects:
  • Severe hypoglycemia
  • Allergic reactions (rash, itching, swelling)
  • Liver function impairment

Precautions:

• Pregnancy and Breastfeeding:
  • Use with caution during pregnancy and breastfeeding. Consult a healthcare provider.
• Kidney and Liver Disease:
  • Dose adjustments may be necessary for patients with renal or hepatic impairment.
• Hypoglycemia Risk:
  • Monitor blood sugar levels regularly, especially during periods of increased stress or illness.

Contraindications:

• Hypersensitivity:
  • Known allergy to glimepiride or other sulfonylureas.
• Type 1 Diabetes:
  • Not indicated for use in type 1 diabetes or diabetic ketoacidosis.