Guaifenesin Salbutamol (Guiacof Plus) 50mg/1mg/5ml Syrup 60ml

Expectorant/Bronchodilator

Certainly! Here is a detailed breakdown for Guaifenesin Salbutamol (Guiacof Plus) 50mg/1mg/5ml Syrup 60ml:

Product Description:

Guaifenesin Salbutamol (Guiacof Plus) 50mg/1mg/5ml Syrup 60ml is a combination medication used primarily for the treatment of respiratory conditions where mucus is thick and difficult to clear, and where bronchodilation (opening of the airways) is needed. It contains Guaifenesin, an expectorant, and Salbutamol, a bronchodilator.

• Guaifenesin (50 mg per 5 ml) helps loosen and thin mucus in the airways, making it easier to cough up and clear from the lungs.

• Salbutamol (1 mg per 5 ml) is a beta-2 adrenergic agonist that works by relaxing the muscles in the airways, allowing them to widen (bronchodilation), thus making breathing easier.

This syrup is typically prescribed for people with chronic respiratory conditions or acute respiratory infections that cause excessive mucus production or difficulty breathing.

Indications:

Guaifenesin Salbutamol (Guiacof Plus) 50mg/1mg/5ml Syrup 60ml is indicated for the following conditions:

1. Chronic Respiratory Diseases:

   • Chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

   • Asthma (as a part of symptomatic management to reduce mucus buildup and improve airflow).

2. Acute Respiratory Infections:

   • Conditions like acute bronchitis and pneumonia, where both airway constriction and mucus production can cause breathing difficulties.

3. Cough and Mucus Production:

   • It helps to relieve symptoms of excessive mucus and congestion, making it easier for individuals to clear their airways.

4. Other Respiratory Conditions: It may also be used for other conditions that cause excessive bronchial secretion and difficulty breathing.

Dosages:

The dosage of Guaifenesin Salbutamol (Guiacof Plus) 50mg/1mg/5ml Syrup should be based on the individual’s age, condition, and response to treatment. Below are typical dosage guidelines:

For Adults:

• Initial dose: 10 ml (100 mg Guaifenesin / 2 mg Salbutamol), taken three to four times daily.

• The maximum daily dose is typically 40 ml (400 mg Guaifenesin / 8 mg Salbutamol).

For Children (age 6-12 years):

• Initial dose: 5-10 ml (50-100 mg Guaifenesin / 1-2 mg Salbutamol), taken two to three times daily.

• Maximum dose: 20 ml per day.

For Children (age 2-5 years):

• Initial dose: 2.5-5 ml (25-50 mg Guaifenesin / 0.5-1 mg Salbutamol), taken two to three times daily.

• Maximum dose: 10 ml per day.

Note: Always follow the specific dosing instructions provided by your doctor or pharmacist, as they may adjust based on the patient's condition and response.

Side Effects:

Guaifenesin Salbutamol (Guiacof Plus), like all medications, can cause side effects. The following are common and more serious side effects that may occur:

Common Side Effects:

• Mild gastrointestinal issues:

  • Nausea

  • Vomiting

  • Upset stomach or indigestion

• Nervousness or restlessness: Common with Salbutamol use, as it can stimulate the nervous system.

• Headache

• Dizziness or lightheadedness

• Dry mouth or throat irritation

• Tremors or shakiness, especially in the hands

• Increased heart rate (tachycardia)

Serious Side Effects (Less common but potentially severe):

• Severe allergic reactions: Including difficulty breathing, swelling of the face, lips, or tongue, and skin rash (signs of anaphylaxis).

• Chest pain or palpitations: A feeling of a racing heart or irregular heartbeat.

• Severe dizziness or fainting.

• Hypokalemia (low potassium levels), which can cause muscle weakness or irregular heart rhythms.

• Respiratory distress: Difficulty breathing or worsening of asthma symptoms.

If any of these serious side effects occur, immediate medical attention should be sought.

Contraindications:

Guaifenesin Salbutamol (Guiacof Plus) should not be used in the following cases:

1. Hypersensitivity (allergic reaction) to Guaifenesin, Salbutamol, or any of the inactive ingredients in the syrup.

2. Severe cardiac conditions, including:

   • Uncontrolled hypertension (high blood pressure).

   • Severe heart disease or arrhythmias (irregular heartbeats).

3. Hyperthyroidism: Salbutamol can exacerbate symptoms of hyperthyroidism, as it can increase the heart rate and metabolic rate.

4. Severe respiratory conditions where beta-agonists may worsen the condition (e.g., certain forms of asthma, COPD) without proper medical supervision.

5. History of bronchospasm or paradoxical bronchoconstriction: Rare, but Salbutamol can, in very rare cases, cause paradoxical tightening of the airways (bronchospasm).

Precautions:

• Pregnancy: The safety of Guiacof Plus during pregnancy has not been fully established, so it should only be used if deemed absolutely necessary by your healthcare provider.

• Breastfeeding: It is unknown whether the active ingredients pass into breast milk. Consult with a healthcare provider before using this product while breastfeeding.

• Renal or Hepatic Impairment: Use caution in individuals with liver or kidney disease. Dosage adjustments may be needed.

• Pre-existing heart conditions: Caution is required in patients with a history of arrhythmias, coronary artery disease, or hypertension.

• Patients with diabetes: Salbutamol may increase blood glucose levels, so individuals with diabetes should be monitored closely.

Important Notes:

• Use only as directed: Guiacof Plus should be used exactly as prescribed. Overuse or misuse, especially in patients with underlying heart conditions, can lead to severe complications.

• Monitor for side effects: Regular monitoring of heart rate, blood pressure, and lung function may be necessary, especially if taking this syrup long-term or at high doses.

• Stay hydrated: Since Guaifenesin works as an expectorant, drinking plenty of fluids may help enhance its effectiveness in clearing mucus.

• Avoid alcohol: Alcohol may increase the sedative effects and interact with the medication, so it’s advisable to avoid it.

Always consult with your healthcare provider before starting treatment with Guaifenesin Salbutamol (Guiacof Plus) to ensure it’s appropriate for your condition and to discuss any potential interactions with other medications you may be taking.