Hydrocortisone Sodium Succinate (Hydrocortibas) 100 mg Powder for Injection IM/IV Vials 10's

Corticosteroid

Storage: 
Store at temperature not exceeding 30°C. Protect from direct sunlight.

Do Not Freeze

Certainly! Here's a detailed overview of Hydrocortisone Sodium Succinate (Hydrocortibas) 100 mg Powder for Injection IM/IV Vials 10's:

Product Description:

Hydrocortisone Sodium Succinate (Hydrocortibas) 100 mg Powder for Injection is a corticosteroid medication used to treat a variety of inflammatory and immune-related conditions. It contains Hydrocortisone Sodium Succinate, which is a water-soluble form of hydrocortisone, a naturally occurring steroid hormone that affects various systems in the body, including the immune system and metabolism. The injectable form of hydrocortisone allows for rapid delivery and effectiveness, especially in emergency or hospital settings.

This medication is typically reconstituted into a solution before being administered through intravenous (IV) or intramuscular (IM) injection. It is available in 100 mg vials, and the vials come in packs of 10.

Indications:

Hydrocortisone Sodium Succinate (Hydrocortibas) is indicated for the treatment of various conditions, including:

• Severe inflammatory conditions, such as:

  • Acute allergic reactions (e.g., severe asthma, anaphylaxis)

  • Rheumatic disorders (e.g., rheumatoid arthritis, lupus)

  • Dermatological conditions (e.g., dermatitis, eczema)

  • Ophthalmic conditions (e.g., uveitis)

  • Inflammation of the gastrointestinal tract (e.g., ulcerative colitis, Crohn’s disease)

• Endocrine disorders like adrenal insufficiency (e.g., Addison’s disease) where the body cannot produce enough corticosteroids.

• Shock associated with adrenal insufficiency or as a treatment for severe infection or injury.

• Post-surgical conditions: For managing inflammation or preventing rejection in transplant patients.

• Autoimmune conditions: To help manage conditions like multiple sclerosis or other systemic autoimmune diseases.

Hydrocortisone is used when a rapid, potent anti-inflammatory effect is needed, especially when oral corticosteroids are not suitable or effective.

Dosage:

The dosage of Hydrocortisone Sodium Succinate (Hydrocortibas) varies depending on the severity of the condition, the patient's age, and their response to treatment. Typical dosages are as follows:

• For acute conditions (e.g., shock, anaphylaxis):

  • Adults: Initially, 100 mg to 500 mg IV/IM, depending on the severity of the condition. The dose may be repeated or adjusted as necessary.

• For inflammatory or autoimmune conditions (e.g., rheumatoid arthritis, lupus):

  • Adults: A typical initial dose is 100 mg IV/IM every 2 to 6 hours, which can be reduced as symptoms improve.

• For adrenal insufficiency (e.g., Addison’s disease):

  • The initial dose is typically 100 mg IV/IM, and this may be followed by maintenance doses of 50 mg every 6 hours, gradually decreasing the dosage as the patient stabilizes.

• For children:

  • Pediatric doses should be carefully adjusted based on the child's weight, age, and condition. The healthcare provider will determine the exact dosage.

Note: Hydrocortisone therapy should be tapered down gradually once the patient stabilizes, particularly in long-term treatments, to avoid withdrawal symptoms or adrenal insufficiency.

Side Effects:

Common side effects of Hydrocortisone Sodium Succinate (Hydrocortibas) may include:

• Injection site reactions (pain, redness, swelling, irritation)

• Fluid retention leading to edema (swelling)

• Increased blood pressure (hypertension)

• Hyperglycemia (high blood sugar levels)

• Increased appetite or weight gain

• Mood swings, including anxiety or irritability

• Insomnia

• Gastrointestinal issues (e.g., nausea, stomach upset, peptic ulcers)

Serious side effects may include:

• Osteoporosis (long-term use)

• Increased risk of infections (due to immunosuppressive effects)

• Cataracts or glaucoma

• Muscle weakness or myopathy with prolonged use

• Psychiatric disorders, including depression, psychosis, or delirium

• Cushing's syndrome (with prolonged high doses, resulting in weight gain, moon face, and thinning skin)

If any severe reactions occur, such as signs of infection or an allergic reaction (e.g., rash, swelling, difficulty breathing), medical attention should be sought immediately.

Contraindications:

Hydrocortisone Sodium Succinate (Hydrocortibas) should not be used in the following situations:

• Hypersensitivity to Hydrocortisone, other corticosteroids, or any of the excipients in the product.

• Systemic fungal infections: Corticosteroids may worsen fungal infections, so they are contraindicated in these conditions.

• Active tuberculosis: Unless used as part of a comprehensive anti-tuberculosis treatment regimen, corticosteroids should not be used in active tuberculosis.

• Untreated bacterial infections: Except in the case of severe infection requiring corticosteroid therapy, Hydrocortisone should not be used as the primary treatment for active infections.

• Peptic ulcers or gastrointestinal bleeding: Corticosteroids can increase the risk of bleeding in the gastrointestinal tract.

• Severe hypertension: Corticosteroids can exacerbate high blood pressure, and should be avoided in cases of poorly controlled hypertension.

Precautions:

• Infections: Use with caution in patients with active or chronic infections, as corticosteroids can suppress the immune response.

• Diabetes: Hydrocortisone may increase blood glucose levels, so close monitoring is required in diabetic patients.

• Cardiovascular diseases: Since corticosteroids can increase blood pressure and cause fluid retention, caution is required in patients with cardiovascular conditions.

• Psychiatric Effects: Prolonged use can lead to psychiatric disturbances. Patients on long-term therapy should be monitored for signs of mental health issues.

• Adrenal Suppression: Long-term use can lead to suppression of the adrenal glands, and discontinuation should be done gradually under medical supervision.

Storage:

• Store the Hydrocortisone Sodium Succinate (Hydrocortibas) Powder for Injection in a cool, dry place at temperatures below 30°C (86°F).

• Keep the vials in their original packaging to protect them from light.

• Do not freeze the product.

• Once reconstituted, the solution should be used immediately or stored in the refrigerator and used within a specified time as indicated by the manufacturer.

This overview provides general information about Hydrocortisone Sodium Succinate (Hydrocortibas) 100 mg Powder for Injection IM/IV Vials 10's. For specific advice tailored to your individual health condition, always consult with a healthcare provider.