Bambang Pharmaceutical Depot Inc.
Ibuprofen (Saphfen) 400mg Tablet 100's
Ibuprofen (Saphfen) 400mg Tablet 100's
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Product Description:
Ibuprofen (Saphfen) 400mg Tablet 100's is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the production of prostaglandins—chemicals in the body that promote inflammation, pain, and fever. Ibuprofen is commonly used for conditions such as arthritis, menstrual pain, muscle aches, headaches, and to manage pain from injuries or dental procedures.
Each tablet contains 400 mg of Ibuprofen, and the product comes in a bottle of 100 tablets. This medication is effective in treating mild to moderate pain and inflammation and is commonly available over-the-counter or with a prescription, depending on the dosage.
Indications:
Ibuprofen (Saphfen) 400mg is indicated for:
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Pain relief: Including pain from conditions like headaches, toothaches, muscle strains, back pain, and minor injuries.
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Fever reduction: Used to lower fever associated with conditions such as the common cold or infections.
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Inflammatory conditions: Such as arthritis, including rheumatoid arthritis and osteoarthritis, to reduce inflammation and associated pain.
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Dysmenorrhea (menstrual pain): Used to relieve pain and discomfort associated with menstruation.
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Post-surgical pain: To manage pain after surgery or dental procedures.
Ibuprofen may also be used off-label for other inflammatory or pain-related conditions under the supervision of a healthcare provider.
Dosage:
The typical dosage of Ibuprofen (Saphfen 400mg) depends on the condition being treated, the patient's age, and their overall health. Below are general guidelines for adults:
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For Pain and Inflammation:
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The usual dose is 400 mg every 4 to 6 hours as needed.
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Maximum daily dose: Do not exceed 1200 mg per day when used over-the-counter. For higher doses, a healthcare provider may recommend up to 2400 mg per day under medical supervision.
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For Fever:
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400 mg every 4 to 6 hours as needed to reduce fever.
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The maximum dose for fever should not exceed 1200 mg per day unless otherwise directed by a doctor.
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For Osteoarthritis or Rheumatoid Arthritis:
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Starting dose: 400 to 800 mg every 6 to 8 hours.
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The maximum dose may go up to 3200 mg per day, but this requires a prescription and careful monitoring due to the risk of side effects.
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Administration: Ibuprofen should be taken with food or a glass of milk to reduce the risk of stomach upset. Swallow the tablet whole with plenty of water.
Side Effects:
Common side effects of Ibuprofen (Saphfen 400mg) may include:
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Upset stomach: Such as indigestion, nausea, or abdominal pain.
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Headache or dizziness.
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Rash or itching.
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Constipation or diarrhea.
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Fatigue or tiredness.
Serious but less common side effects include:
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Gastrointestinal bleeding or ulcers: Symptoms may include stomach pain, black stools, or vomiting blood.
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Kidney problems: Symptoms may include reduced urination, swelling, or weight gain.
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Liver damage: Symptoms include yellowing of the skin or eyes (jaundice), dark urine, or unusual fatigue.
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Allergic reactions: Such as swelling of the face, lips, tongue, or throat, difficulty breathing, or anaphylaxis.
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Heart issues: Increased risk of heart attack or stroke, particularly with prolonged use or in those with pre-existing heart conditions.
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High blood pressure: Chronic use can contribute to hypertension.
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Skin reactions: Serious reactions such as peeling skin, blistering, or lesions (such as Stevens-Johnson syndrome).
If any of these serious side effects occur, seek immediate medical attention.
Contraindications:
Ibuprofen (Saphfen 400mg) should not be used in the following situations:
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Hypersensitivity: To ibuprofen or other NSAIDs (such as aspirin, naproxen), which may cause allergic reactions.
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Active gastrointestinal bleeding or ulcers: Ibuprofen can irritate the stomach lining and increase the risk of bleeding and ulceration.
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Severe liver or kidney disease: Since ibuprofen is metabolized by the liver and excreted by the kidneys, it should be avoided in people with severe liver or kidney problems.
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Severe heart failure: Ibuprofen can worsen heart failure by causing fluid retention and increasing blood pressure.
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Pregnancy: Third trimester: Ibuprofen is contraindicated in the third trimester of pregnancy as it can cause premature closure of the ductus arteriosus in the fetus, leading to fetal complications. It should only be used in the first and second trimesters if necessary and under medical supervision.
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Breastfeeding: Although Ibuprofen is generally considered safe in breastfeeding, consult with a healthcare provider before use.
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Asthma with nasal polyps: In individuals who have asthma, nasal polyps, or chronic respiratory conditions, ibuprofen can cause severe allergic reactions.
Precautions:
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Hypertension: Caution is required in patients with high blood pressure as NSAIDs can elevate blood pressure and worsen hypertension.
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Elderly: Older adults are more likely to experience side effects like gastrointestinal bleeding or kidney issues and may need a lower dose or more frequent monitoring.
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Heart disease: Use with caution in individuals with cardiovascular disease, as prolonged use can increase the risk of heart attacks or strokes.
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Chronic alcohol use: Increases the risk of gastrointestinal bleeding and liver damage when combined with ibuprofen.
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Dehydration: Ensure adequate hydration as dehydration can increase the risk of kidney damage.
Pregnancy and breastfeeding:
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Pregnancy: Avoid during the third trimester. For first and second trimesters, use only if necessary and under healthcare supervision.
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Breastfeeding: Generally considered safe in small doses but should be used cautiously.
Important Note: Always follow the dosage and instructions provided by your healthcare provider or pharmacist. Overuse or prolonged use of Ibuprofen (Saphfen 400mg) can lead to significant side effects, including gastrointestinal issues, kidney damage, and cardiovascular risks. If you experience any serious side effects or have concerns about taking ibuprofen, contact your healthcare provider immediately.
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