Losartan Potassium (Saphlor 100) 100mg Film-Coated Tablets are used primarily to treat high blood pressure and related conditions. Here are the primary indications and uses:
Indications and Uses
Hypertension (High Blood Pressure):
Treatment: Losartan is used to lower blood pressure in adults and children over 6 years of age. It helps to reduce the risk of stroke and heart attack by managing blood pressure levels.
Heart Failure:
Management: Used in combination with other medications to manage heart failure in patients who cannot tolerate ACE inhibitors.
Diabetic Nephropathy:
Chronic Kidney Disease: Helps to protect the kidneys in patients with type 2 diabetes who have high blood pressure and evidence of kidney damage.
Stroke Risk Reduction:
Prevention: Reduces the risk of stroke in patients with hypertension and left ventricular hypertrophy (thickening of the heart muscle).
Mechanism of Action
Angiotensin II Receptor Blocker (ARB): Losartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict (narrow). By inhibiting this action, Losartan helps relax blood vessels, allowing blood to flow more easily, which lowers blood pressure and reduces strain on the heart.
Dosage and Administration
Dosage:
Hypertension: The usual starting dose is 50mg once daily. Depending on the patient's response and tolerance, the dose may be increased to 100mg once daily.
Heart Failure and Diabetic Nephropathy: Dosage may be adjusted based on the condition being treated and the patient's response.
Administration: Take the tablet orally with a glass of water. It can be taken with or without food.
Instructions for Use
Regular Use:
Take the tablet at the same time each day to help maintain consistent blood pressure control.
Missed Dose:
If a dose is missed, take it as soon as possible. If it is close to the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses.
Precautions
Allergic Reactions: Ensure there are no known allergies to Losartan or other ARBs.
Pregnancy and Breastfeeding: Losartan should not be used during pregnancy due to potential harm to the fetus. Consult a healthcare provider if breastfeeding.
Kidney Function: Use with caution in patients with renal impairment, and monitor kidney function regularly.
Liver Function: Adjustments may be necessary for patients with liver impairment.
Side Effects
Common: Dizziness, headache, fatigue, and back pain.
Serious: Rare but may include severe allergic reactions, such as rash, swelling, or difficulty breathing. Kidney problems or very low blood pressure could also occur. Seek medical attention if serious side effects occur.
Storage
Storage: Store tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.
Losartan Potassium (Saphlor 100) 100mg Film-Coated Tablets are effective in managing high blood pressure and other related conditions. Proper adherence to the prescribed dosage and usage instructions helps to ensure effectiveness and minimize potential side effects.
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