Metformin Hydrochloride (Glycemet) 500mg FC Oral Hypoglycemic Tablets 100's

Generic Name: Metformin Hydrochloride

Brand Name: Glycemet

Strength: 500mg

Form: Tablet

Manufacturer: 

Imported and Distributed by: 

Classification: Oral Hypoglycemic

Indication/Uses: 

Metformin Hydrochloride (Glycemet) 500mg FC Oral Hypoglycemic Tablets are a widely used medication in the management of type 2 diabetes mellitus. Here are the primary indications and uses for this medication:

Indications and Uses

1. Type 2 Diabetes Mellitus:

   • Blood Glucose Control: Metformin is used to help control blood glucose levels in individuals with type 2 diabetes. It is often prescribed when diet and exercise alone are insufficient to manage blood sugar levels.
   • First-Line Therapy: Metformin is typically the first-line medication for type 2 diabetes due to its effectiveness and safety profile.

2. Insulin Sensitivity:

   • Improving Insulin Sensitivity: It helps improve insulin sensitivity and decrease insulin resistance, which can enhance the body’s ability to use glucose effectively.

3. Weight Management:

   • Support: Metformin may help with weight management in individuals with type 2 diabetes. It is often associated with weight neutrality or modest weight loss.

4. Polycystic Ovary Syndrome (PCOS) (Off-label use):

   • Management: Metformin is sometimes used off-label to manage symptoms of PCOS, particularly in cases of insulin resistance or abnormal glucose metabolism.

Dosage and Administration

• Dosage: The typical starting dose for adults is 500 mg to 1000 mg, taken two to three times daily with meals. The dose can be gradually increased based on blood glucose levels and tolerance, up to a maximum of 2000 mg to 3000 mg per day, divided into two or three doses.
• Administration: The tablets should be swallowed whole with a glass of water, preferably with meals to minimize gastrointestinal side effects.

Precautions

• Renal Function: Metformin should be used with caution in patients with impaired renal function. Regular monitoring of kidney function is recommended.
• Lactic Acidosis: There is a rare risk of lactic acidosis, especially in patients with significant renal impairment, liver disease, or severe infections. Symptoms include unusual fatigue, muscle pain, and difficulty breathing.
• Contrast Agents: Avoid using metformin in conjunction with certain contrast agents used in imaging procedures that can affect renal function.

Side Effects

• Common: Gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal discomfort are common, especially at the beginning of treatment. These symptoms often improve over time.
• Serious: Rare but serious side effects include lactic acidosis, severe allergic reactions, and vitamin B12 deficiency. Regular monitoring and evaluation are important to detect any potential issues.

Monitoring

• Blood Glucose Levels: Regular monitoring of blood glucose levels is necessary to assess the effectiveness of the medication and make any necessary dosage adjustments.
• Kidney Function: Periodic assessment of renal function is recommended, especially if there are signs of renal impairment.

Metformin Hydrochloride (Glycemet) 500mg FC Oral Hypoglycemic Tablets are used to manage type 2 diabetes by improving insulin sensitivity and controlling blood glucose levels. Adherence to dosage guidelines and regular monitoring are key to optimizing treatment outcomes and minimizing potential side effects.