Methyldopa (Mydopa) 250mg Film Coated Tablet 100's

Generic Name: Methyldopa

Brand Name: Mydopa

Strength: 250mg

Form: Tablet

Manufacturer:

Imported and Distributed by:

Classification: Antihypertensive

Indication/Uses: 

Methyldopa (Mydopa) 250mg Film Coated Tablets are primarily used to manage high blood pressure (hypertension). Here are the main indications and uses for this medication:

Indications and Uses

1. Hypertension:

   • Blood Pressure Control: Methyldopa is used to treat high blood pressure. It works as an antihypertensive agent by stimulating alpha-2 adrenergic receptors in the brain, which leads to reduced nerve signals that cause blood vessels to constrict, thereby lowering blood pressure.

2. Hypertension in Pregnancy:

   • Gestational Hypertension: Methyldopa is sometimes used to manage hypertension in pregnant women, particularly when other medications are contraindicated or not suitable. It is considered relatively safe during pregnancy compared to some other antihypertensive medications.

Dosage and Administration

• Dosage: The usual starting dose for adults is 250 mg taken 2-3 times daily. The dose may be gradually increased based on blood pressure response and tolerability, up to a maximum of 3000 mg per day, divided into several doses.
• Administration: The tablets should be swallowed whole with a glass of water. It is often taken with food to reduce gastrointestinal discomfort.

Precautions

• Liver Function: Use with caution in patients with liver impairment, as methyldopa can affect liver function. Regular liver function tests may be necessary.
• Renal Function: Caution is advised in patients with renal impairment. Dose adjustments may be needed based on renal function.
• Orthostatic Hypotension: Methyldopa can cause orthostatic hypotension (a sudden drop in blood pressure when standing up), so patients should be advised to rise slowly from sitting or lying positions.
• Other Medications: Inform your healthcare provider of all other medications you are taking, as methyldopa can interact with other drugs.

Side Effects

• Common: Side effects may include drowsiness, dizziness, dry mouth, and fatigue. Gastrointestinal symptoms such as nausea and vomiting may also occur.
• Serious: Rare but serious side effects include liver dysfunction, hemolytic anemia, and severe allergic reactions. Regular monitoring is recommended to detect any serious adverse effects.

Monitoring

• Blood Pressure: Regular monitoring of blood pressure is essential to evaluate the effectiveness of the medication and make dosage adjustments as needed.
• Liver Function: Periodic liver function tests are recommended to monitor for potential liver-related side effects.
• Blood Tests: Routine blood tests may be necessary to check for anemia and other potential side effects.

Methyldopa (Mydopa) 250mg Film Coated Tablets are used primarily for managing hypertension, including in pregnant women. Proper dosing, regular monitoring, and adherence to medical advice are crucial for effective treatment and minimizing potential side effects.