Omeprazole 40mg Lyophilized Powder For Injection (IV) Vial 10's

Generic Name: OMEPRAZOLE

Brand Name: OMESENZ

Strength: 40mg

Form: POWDER FOR INJECTION

Manufacturer: REYOUNG PHARMACEUTICAL CO., LTD.

Imported and Distributed by: PHARMAESSENCE, INC.

Classification: PROTON PUMP INHIBITOR

Indication/Uses: 

1. Gastroesophageal Reflux Disease (GERD)

   • Usage: Omeprazole IV is indicated for the treatment of gastroesophageal reflux disease (GERD) when oral therapy is not possible.
   • Importance: GERD is a chronic condition where stomach acid frequently flows back into the esophagus, leading to symptoms like heartburn and acid regurgitation.

2. Erosive Esophagitis

   • Usage: Indicated for the treatment of erosive esophagitis confirmed by endoscopy when oral administration of omeprazole is not feasible.
   • Importance: Erosive esophagitis is inflammation and damage to the esophageal lining caused by stomach acid, which can lead to severe complications if untreated.

3. Peptic Ulcer Disease

   • Usage: Used for the treatment of active duodenal ulcers and gastric ulcers in patients who cannot take oral medications.
   • Importance: Peptic ulcers are sores that develop on the lining of the stomach, lower esophagus, or small intestine due to excessive stomach acid.

4. Zollinger-Ellison Syndrome

   • Usage: Indicated for the management of Zollinger-Ellison syndrome, a condition where the stomach produces too much acid due to tumors in the pancreas or duodenum.
   • Importance: This rare condition can cause severe ulcers and other gastrointestinal issues.

5. Upper Gastrointestinal Bleeding

   • Usage: Utilized in the prevention and treatment of upper gastrointestinal bleeding in critically ill patients or those with known peptic ulcer disease.
   • Importance: Rapid control of stomach acid can prevent further bleeding and promote healing.

Uses

1. Acid Reduction

   • Mechanism: Omeprazole inhibits the hydrogen-potassium ATPase enzyme system of the gastric parietal cells, reducing gastric acid secretion.
   • Administration: Administered intravenously when oral intake is not possible or practical, typically in hospital settings.

2. Symptom Relief

   • Clinical Benefit: Provides relief from symptoms associated with excess stomach acid, such as heartburn, indigestion, and pain from ulcers.
   • Outcome: Effective acid suppression helps promote healing of the esophagus, stomach, and duodenum, and alleviates discomfort.

3. Healing and Prevention

   • Clinical Benefit: Helps in the healing of existing ulcers and prevents the formation of new ones by reducing gastric acidity.
   • Outcome: Lowered acidity protects the gastrointestinal lining and reduces the risk of complications like perforation or bleeding.

Dosage and Administration

• Initial Dose: Typically, the dosage is 40mg administered once daily by intravenous infusion over 20-30 minutes.
• Duration: The duration of treatment depends on the specific condition and patient response. Transition to oral therapy is recommended as soon as feasible.