Potassium Citrate (Saphtrate) 1.080g (10mEq) Extended Release Tablets are used to manage and prevent conditions related to potassium and citrate imbalances. Here are the main indications and uses:
Indications and Uses
Potassium Deficiency:
Supplementation: Used to prevent or treat potassium deficiency (hypokalemia) in patients who may need potassium supplementation due to dietary restrictions, chronic diseases, or medications that deplete potassium.
Renal Stone Prevention:
Kidney Stones: Helps prevent the formation of kidney stones, particularly calcium-based stones, by increasing urinary citrate levels. Citrate binds to calcium, reducing its availability to form stones.
Metabolic Alkalosis:
Acid-Base Balance: Used to correct metabolic alkalosis (a condition where the blood is too alkaline) by providing potassium and citrate, which helps restore normal acid-base balance.
Management of Certain Urinary Conditions:
Urinary Health: Used in conditions that benefit from increased urinary citrate, which can help prevent crystal formation and urinary tract complications.
Mechanism of Action
Potassium Supplement: Provides potassium, which is essential for normal cell function, nerve impulses, muscle contractions, and overall electrolyte balance.
Citrate Component: Increases urinary citrate levels, which helps prevent the formation of calcium-based kidney stones by binding calcium in the urine and reducing stone formation.
Dosage and Administration
Typical Dosage: The usual dosage is one extended-release tablet (1.080g or 10mEq) taken orally, usually once or twice daily. Dosage may vary based on individual needs and medical conditions.
Administration: Tablets should be taken with food and a full glass of water to help reduce gastrointestinal irritation and ensure proper absorption.
Precautions
Renal Function: Use with caution in patients with renal impairment, as potassium levels can become elevated if the kidneys cannot properly excrete potassium.
Acid-Base Balance: Monitor patients for signs of metabolic acidosis or alkalosis and adjust dosage accordingly.
Drug Interactions: Be aware of potential interactions with other medications, particularly those affecting potassium levels or renal function.
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