Ranitidine Hydrochloride (Gastrosaph AB150) 150mg Film Coated Tablet 100's

Generic Name: Ranitidine Hydrochloride

Brand Name: Gastrosaph AB150

Strength: 150mg

Form: Tablet

Manufacturer:

Imported and Distributed by:

Classification: H2- Receptor Antagonist

Indication/Uses:

Ranitidine Hydrochloride (Gastrosaph AB150) 150mg Film-Coated Tablets are used primarily to treat conditions related to excessive stomach acid. Here are the primary indications and uses for this medication:

Indications and Uses

1. Gastric Ulcers:

   • Treatment and Prevention: Used to treat active gastric ulcers and help prevent their recurrence by reducing stomach acid production, which promotes healing.

2. Duodenal Ulcers:

   • Management: Effective in treating duodenal ulcers and preventing their recurrence by decreasing acid secretion in the stomach.

3. Gastroesophageal Reflux Disease (GERD):

   • Symptom Relief: Helps manage GERD by reducing stomach acid and preventing acid reflux into the esophagus, which alleviates symptoms like heartburn and regurgitation.

4. Zollinger-Ellison Syndrome:

   • Excess Acid Production: Used in the treatment of Zollinger-Ellison syndrome, a condition characterized by excessive gastric acid production.

5. Preoperative Medication:

   • Acid Reduction: Sometimes administered before surgical procedures to reduce the risk of acid aspiration and related complications.

Mechanism of Action

• H2-Receptor Antagonism: Ranitidine is an H2 receptor antagonist that blocks histamine H2 receptors in the stomach lining. This reduces the production of gastric acid, which helps to alleviate symptoms of acid-related conditions and promotes healing of ulcers.

Dosage and Administration

• Typical Dosage:
  • Gastric and Duodenal Ulcers: Usually, the recommended dose is 150mg twice daily or 300mg once daily, depending on the condition and patient response.
  • GERD: Often, 150mg twice daily is used to manage symptoms.
  • Zollinger-Ellison Syndrome: Higher doses may be required based on the severity of the condition.
• Administration: Tablets should be taken orally with or without food. Swallow the tablets whole; do not crush or chew.

Precautions

• Renal Impairment: Use with caution in patients with renal impairment as dosage adjustments may be necessary.
• Allergies: Check for known allergies to ranitidine or other H2 receptor antagonists.
• Drug Interactions: Be aware of potential drug interactions, especially with medications that are affected by changes in stomach pH or metabolism.

Side Effects

• Common: Headache, dizziness, gastrointestinal disturbances such as constipation or diarrhea.
• Serious: Rare but serious side effects may include allergic reactions, liver enzyme changes, and blood disorders such as thrombocytopenia or agranulocytosis.

Monitoring

• Regular Monitoring: Monitor for potential side effects, especially in patients with prolonged or high-dose treatment.
• Renal Function: Check renal function regularly in patients with compromised kidney function or those on long-term therapy.

Ranitidine Hydrochloride (Gastrosaph AB150) 150mg Film-Coated Tablets are used to manage a variety of conditions related to excessive stomach acid, including ulcers and GERD. Proper dosage, adherence to administration guidelines, and monitoring are essential for effective treatment and minimizing potential side effects.