Aciclovir (Xyclovirax) 800mg Anti Viral Tablets 20's

Description:
Used to treat infections caused by certain types of viruses. It treats cold sores around the mouth (caused by herpes simplex), shingles (caused by herpes zoster), and chickenpox. This medication is also used to treat outbreaks of genital herpes.

Product Description:

Aciclovir (Xyclovirax) 800mg Anti-Viral Tablets are used to treat infections caused by the herpes virus, including herpes simplex and varicella-zoster viruses. Aciclovir is an antiviral medication that works by inhibiting the replication of viral DNA, preventing the virus from multiplying in the body. It is most commonly used for treating cold sores, genital herpes, shingles, and chickenpox.

Each tablet of Xyclovirax contains 800mg of Aciclovir, and the packaging contains 20 tablets.

Key Features:

• Active Ingredient: Aciclovir 800mg.

• Formulation: Oral tablet, to be taken by mouth.

• Mechanism of Action: Inhibits viral DNA synthesis by interfering with viral DNA polymerase.

• Indications: Used to treat various herpes virus infections, including cold sores, genital herpes, shingles, and chickenpox.

• Packaging: Available in 20-tablet packs.

Indications:

Aciclovir (Xyclovirax) 800mg tablets are indicated for the treatment of:

1. Herpes Simplex Virus (HSV) Infections:

   • Cold sores (Herpes labialis).

   • Genital herpes (Primary and recurrent episodes).

2. Varicella-Zoster Virus (VZV) Infections:

   • Shingles (Herpes zoster).

   • Chickenpox (Varicella) in children and adults.

3. Prevention of HSV Infections:

   • To prevent recurrent genital herpes in immunocompromised individuals, such as those with HIV/AIDS or organ transplant recipients.

4. Other Herpesvirus Infections:

   • In certain circumstances, Aciclovir is used for other viral infections caused by herpes simplex or varicella-zoster in immunocompromised patients.

Dosage:

The dosage of Aciclovir (Xyclovirax) 800mg tablets varies depending on the type and severity of the infection:

• For Herpes Simplex Virus (Cold Sores):

  • Adults: 200mg to 400mg every 4 hours (5 times daily) for 5 to 10 days.

• For Genital Herpes (Primary Episode):

  • Adults: 400mg three times daily for 5 to 10 days.

• For Recurrent Genital Herpes:

  • Adults: 400mg three times daily for 5 days.

• For Shingles (Herpes Zoster):

  • Adults: 800mg five times daily for 7 to 10 days.

• For Chickenpox:

  • Adults and children ≥ 12 years: 800mg four times daily for 5 days.

• For Prevention of Recurrent Herpes:

  • Adults: 400mg twice daily (can vary depending on patient needs and healthcare provider's advice).

Administration:

• Take tablets with water at the prescribed dosage.

• The tablets can be taken with or without food.

• Missed Dose: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses to make up for a missed dose.

Side Effects:

Common side effects of Aciclovir (Xyclovirax) may include:

• Headache.

• Nausea or vomiting.

• Diarrhea.

• Fatigue.

• Dizziness.

• Rash.

Serious side effects, though rare, may include:

• Kidney problems: Symptoms like swelling, unusual tiredness, or changes in urination.

• Severe allergic reactions: Rash, itching, swelling of the face or throat, difficulty breathing.

• Neurological symptoms: Confusion, hallucinations, seizures (more common in patients with kidney problems or older adults).

• Blood disorders: Low white blood cell count (neutropenia), or low platelet count (thrombocytopenia), which may lead to bruising or infections.

If any of these serious side effects occur, seek immediate medical attention.

Contraindications:

Aciclovir (Xyclovirax) 800mg tablets should not be used in the following situations:

1. Hypersensitivity to Aciclovir or any of its components.

2. Severe renal (kidney) impairment: Special care is needed in patients with kidney disease. Dosing adjustments may be required.

3. Pregnancy: While Aciclovir is considered safe for use during pregnancy, it should only be used if clearly needed and prescribed by a healthcare provider.

4. Breastfeeding: Aciclovir is excreted in breast milk, but it is generally considered safe for short-term use. Consult a doctor before using during breastfeeding.

Warnings and Precautions:

• Kidney Function: Aciclovir can affect kidney function, especially in patients with renal impairment or those taking other drugs that impact the kidneys. Kidney function should be monitored during treatment.

• Hydration: Adequate hydration is important during treatment to help prevent kidney problems.

• Elderly Patients: Elderly patients may be at greater risk of kidney issues and neurological side effects, especially if they have underlying kidney disease.

• Avoid Contact with Eyes: Aciclovir tablets are intended for oral use and should not be applied to the eyes. For eye infections, use an appropriate ophthalmic formulation of Aciclovir.

• Neurological Side Effects: In rare cases, confusion, hallucinations, or seizures may occur, especially in patients with kidney problems or in elderly patients.

• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting treatment with Aciclovir.

Drug Interactions:

Aciclovir (Xyclovirax) may interact with other medications, including:

• Probenecid: This drug can increase the levels of Aciclovir in the blood by reducing its excretion by the kidneys, which may increase the risk of side effects.

• Mycophenolate mofetil: Used in organ transplant patients, it may increase the risk of kidney problems when used with Aciclovir.

• Other nephrotoxic drugs: Caution should be used when combining Aciclovir with other drugs that can affect kidney function, such as NSAIDs or aminoglycoside antibiotics.

Always inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, to avoid potential interactions.

Storage:

• Store Aciclovir (Xyclovirax) tablets at room temperature (15°C to 30°C).

• Protect from moisture and direct sunlight.

• Keep the medication in its original packaging and out of the reach of children.

• Do not use after the expiry date printed on the packaging.

Conclusion:

Aciclovir (Xyclovirax) 800mg tablets are an effective antiviral treatment for various herpesvirus infections, including cold sores, genital herpes, shingles, and chickenpox. They work by inhibiting viral DNA replication, preventing the virus from multiplying. However, caution should be exercised in patients with renal impairment, and it should not be used during pregnancy or breastfeeding unless deemed necessary by a healthcare provider. Always follow your healthcare provider's instructions for the correct dosage and seek immediate medical attention if serious side effects occur.