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Bambang Pharmaceutical Depot Inc.

Carvedilol (Carvesaph) 25mg Film Coated Tablet 30's

Carvedilol (Carvesaph) 25mg Film Coated Tablet 30's

Regular price ₱240.00
Regular price ₱480.00 Sale price ₱240.00
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Description:
used to treat high blood pressure and prevent angina, heart disease and stroke.

Product Description:

Carvedilol (Carvesaph) 25mg Film-Coated Tablets are a medication used primarily for hypertension (high blood pressure) and heart failure. Carvedilol is a beta-blocker with additional alpha-blocking properties. By blocking both beta-adrenergic and alpha-1 adrenergic receptors, it helps to lower heart rate, reduce blood pressure, and improve heart function. It is often prescribed to reduce the risk of cardiovascular events and improve symptoms in people with heart-related conditions.

Each tablet of Carvedilol (Carvesaph) contains 25mg of Carvedilol in a film-coated form for easy swallowing, and the packaging contains 30 tablets.

Key Features:

  • Active Ingredient: Carvedilol 25mg per tablet.

  • Formulation: Film-coated tablet, designed to be taken orally.

  • Mechanism of Action: Dual-action as a beta-blocker (reduces heart rate and blood pressure) and an alpha-blocker (improves blood vessel dilation, lowering blood pressure).

  • Indications: Used for the treatment of hypertension, heart failure, and post-myocardial infarction (after heart attack).

  • Packaging: Available in 30 tablets per pack.

Indications:

Carvedilol (Carvesaph) 25mg tablets are indicated for the treatment of:

  1. Hypertension (High Blood Pressure):

    • Carvedilol is used as an antihypertensive agent to lower blood pressure in individuals with hypertension.

  2. Heart Failure:

    • It is prescribed to improve heart function in people with heart failure, reducing symptoms like shortness of breath and fluid retention.

  3. Post-Myocardial Infarction (Post-Heart Attack):

    • Carvedilol is used to reduce the risk of heart failure and cardiovascular events after a heart attack by lowering blood pressure and reducing the workload on the heart.

  4. Angina:

    • Carvedilol may be used in combination with other treatments to manage angina (chest pain).

  5. Prevention of Cardiovascular Events:

    • It is used to lower the risk of heart attacks, strokes, and other complications in high-risk patients with conditions like coronary artery disease.

Dosage:

The recommended dosage of Carvedilol (Carvesaph) 25mg tablets can vary depending on the specific condition being treated:

  • For Hypertension (High Blood Pressure):

    • Starting dose: 12.5mg once daily.

    • Maintenance dose: The dose can be gradually increased to 25mg twice daily, depending on the patient's response and tolerance.

  • For Heart Failure:

    • Starting dose: 3.125mg twice daily.

    • Maintenance dose: Gradually increased to 25mg twice daily based on the patient's response.

  • For Post-Myocardial Infarction (Post-Heart Attack):

    • Starting dose: 6.25mg twice daily.

    • Maintenance dose: The dose can be increased to 25mg twice daily, based on patient tolerance.

Administration:

  • Take the tablet with food to reduce the risk of dizziness or lightheadedness.

  • Swallow the tablet whole with a glass of water; do not crush or chew the tablet.

  • Take at the same time each day to help remember.

Note: The dosage may need adjustment based on your doctor's recommendations, especially for individuals with liver or kidney problems.

Side Effects:

Common side effects of Carvedilol (Carvesaph) 25mg tablets include:

  • Dizziness or lightheadedness (especially when standing up quickly).

  • Fatigue or tiredness.

  • Low blood pressure (hypotension), which can cause dizziness, fainting, or lightheadedness.

  • Slow heart rate (bradycardia).

  • Diarrhea or nausea.

  • Weight gain (in the case of heart failure treatment).

  • Cold hands or feet (due to blood flow changes).

Serious side effects, although rare, may include:

  • Severe allergic reactions (rash, itching, swelling of the face, lips, or tongue, difficulty breathing).

  • Heart block (severe slowing of the heart rate or irregular heart rhythms).

  • Liver problems: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, and stomach pain.

  • Shortness of breath or worsening of heart failure.

If any serious side effects occur, seek immediate medical attention.

Contraindications:

Carvedilol (Carvesaph) 25mg should not be used in the following situations:

  1. Hypersensitivity to Carvedilol or any of its ingredients.

  2. Severe bradycardia (slow heart rate) or heart block (a condition where electrical impulses in the heart are delayed or blocked).

  3. Severe liver disease (cirrhosis or active hepatitis).

  4. Severe asthma or chronic obstructive pulmonary disease (COPD) with bronchospasm.

  5. Cardiogenic shock (a condition where the heart cannot pump enough blood to meet the body’s needs).

  6. Severe hypotension (very low blood pressure).

  7. Pregnancy: Not recommended during pregnancy unless absolutely necessary and prescribed by a doctor.

  8. Breastfeeding: Should be used with caution in breastfeeding women, as it is not known whether Carvedilol passes into breast milk.

Warnings and Precautions:

  • Heart Rate Monitoring: Carvedilol should be used with caution in patients with heart conditions, as it can lower heart rate significantly.

  • Liver Function: Monitor liver function regularly in patients with liver disease or liver function impairment.

  • Discontinuation: Do not suddenly stop taking Carvedilol without consulting your doctor, as it may worsen your heart condition or cause a sudden increase in blood pressure. The dose should be gradually reduced under a doctor's supervision.

  • Respiratory Issues: Use cautiously in patients with a history of asthma or chronic obstructive pulmonary disease (COPD) due to the risk of exacerbating bronchospasm.

  • Diabetes: Carvedilol can mask the symptoms of low blood sugar (hypoglycemia), so patients with diabetes should monitor their blood sugar levels carefully.

Drug Interactions:

Carvedilol (Carvesaph) may interact with other medications, including:

  • Other antihypertensive medications: May increase the risk of low blood pressure (hypotension).

  • Calcium channel blockers (e.g., verapamil, diltiazem): May enhance the negative effects on heart rate and blood pressure.

  • Insulin or other diabetic medications: May mask the symptoms of hypoglycemia (low blood sugar).

  • Antiarrhythmic drugs: Can increase the risk of heart rhythm problems.

  • Rifampin (an antibiotic): May reduce Carvedilol levels in the blood.

  • Cimetidine (a medication for ulcers): May increase Carvedilol levels, increasing the risk of side effects.

  • CYP2D6 inhibitors: Such as fluoxetine (an antidepressant), may increase Carvedilol levels.

Storage:

  • Store Carvedilol (Carvesaph) tablets at room temperature (15°C to 30°C).

  • Keep the tablets in their original packaging, away from moisture, heat, and direct sunlight.

  • Keep out of the reach of children.

  • Do not use after the expiry date printed on the packaging.

Conclusion:

Carvedilol (Carvesaph) 25mg is an effective medication for treating hypertension, heart failure, and reducing the risk of further heart-related complications after a heart attack. It is also useful in preventing cardiovascular events in high-risk patients. However, it must be used with caution in patients with respiratory conditions, liver disease, and those on other medications that may interact with Carvedilol. Regular monitoring by a healthcare provider is important to ensure the drug is working effectively and safely.

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