Cefalexin is used to treat infections caused by susceptible bacteria. It works by interfering with the formation of the bacteria's cell wall, which results in its rupture and the death of the bacteria.
Preoperative Prophylaxis:
In some cases, cefalexin may be used as a preventive measure before surgical procedures to reduce the risk of postoperative infections.
Mechanism of Action:
Cefalexin inhibits the synthesis of the bacterial cell wall by binding to penicillin-binding proteins (PBPs), which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. This results in cell lysis and death of the bacteria.
Dosage and Administration:
Dosage:
The typical adult dose for treating infections is 500mg every 6 to 12 hours, depending on the severity and type of infection.
Pediatric dosing is based on weight and the specific infection being treated.
Administration:
Cefalexin capsules should be taken orally, and it's essential to complete the full course of therapy as prescribed to avoid bacterial resistance.
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