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Cefuroxime Axetil (SQcef) 250mg/5ml Powder for Suspension Antibacterial 50ml
Cefuroxime Axetil (SQcef) 250mg/5ml Powder for Suspension Antibacterial 50ml
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250mg/5ml Powder for Suspension
ANTIBACTERIAL
Certainly! Here’s the detailed information for Cefuroxime Axetil (SQcef) 250mg/5ml Powder for Suspension Antibacterial 50ml:
Product Description:
SQcef 250mg/5ml Powder for Suspension is an antibiotic formulation containing Cefuroxime Axetil, a second-generation cephalosporin antibiotic. This medication is designed to treat a wide range of bacterial infections by inhibiting the growth of bacteria. It is reconstituted into a suspension for oral administration, making it suitable for both adults and children.
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Cefuroxime Axetil is the oral prodrug of Cefuroxime, which is converted in the body to the active form of the antibiotic, Cefuroxime. It is effective against both Gram-positive and Gram-negative bacteria.
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SQcef provides a convenient 50ml suspension with 250mg of Cefuroxime Axetil per 5ml for easier dosing.
Indications:
SQcef 250mg/5ml Powder for Suspension is indicated for the treatment of various bacterial infections, including:
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Upper respiratory tract infections (URIs):
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Pharyngitis (sore throat)
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Tonsillitis
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Sinusitis
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Otitis media (middle ear infection)
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Lower respiratory tract infections (LRIs):
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Bronchitis
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Pneumonia
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Urinary tract infections (UTIs):
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Cystitis (bladder infection)
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Pyelonephritis (kidney infection)
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Skin and soft tissue infections:
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Impetigo
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Cellulitis
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Bone and joint infections: For certain types of osteomyelitis or septic arthritis.
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Gonorrhea: A bacterial infection transmitted sexually.
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Pre-surgical prophylaxis: To prevent infections during surgery, especially in clean surgeries.
Dosage:
The exact dosage of SQcef 250mg/5ml Powder for Suspension depends on the severity of the infection, the patient’s age, and other individual factors like renal function. Below are general guidelines:
For Adults:
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Typical dose: 250mg to 500mg (5ml to 10ml suspension) twice a day for 7-10 days, depending on the infection type and severity.
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For uncomplicated urinary tract infections: 250mg twice a day.
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For upper respiratory infections or skin infections: 500mg twice a day.
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For gonorrhea: A single dose of 1g (20ml suspension).
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For Children (over 3 months of age):
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Typical dose: 10mg to 20mg per kg body weight per day, divided into 2 doses (morning and evening).
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For ear infections (otitis media): 20mg/kg/day in 2 divided doses.
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For respiratory tract infections: 15mg/kg/day in 2 divided doses.
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Note: It is essential to reconstitute the powder properly according to the instructions on the label and to use an appropriate measuring device to ensure accurate dosing.
Side Effects:
SQcef 250mg/5ml Powder for Suspension is generally well tolerated, but like all medications, it may cause some side effects. Common and serious side effects may include:
Common Side Effects:
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Gastrointestinal issues: Mild nausea, vomiting, diarrhea, or stomach upset.
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Rash: A mild skin rash may occur in some individuals.
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Headache or dizziness: These may be less common but can occur in some patients.
Serious Side Effects:
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Severe allergic reactions: These include anaphylaxis, swelling of the face or throat, difficulty breathing, and hives. Seek immediate medical attention if these occur.
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Severe diarrhea: If diarrhea is severe or persistent, it could be a sign of Clostridium difficile-associated diarrhea (CDAD), a severe gut infection.
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Liver problems: Signs of liver dysfunction such as yellowing of the skin or eyes (jaundice) and unusual dark urine.
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Blood disorders: Rarely, low white blood cell count (leukopenia) or low platelet count (thrombocytopenia) can occur, leading to increased risk of infections or bleeding.
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Severe allergic reactions: Itching, swelling, or difficulty breathing (anaphylaxis).
Very Rare Side Effects:
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Seizures: Especially in patients with pre-existing renal conditions or those receiving high doses.
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Nephrotoxicity: Renal toxicity may occur, especially in patients with pre-existing kidney issues or when taken with other nephrotoxic drugs.
If any of these serious side effects occur, the medication should be stopped immediately, and a healthcare provider should be contacted.
Contraindications:
SQcef 250mg/5ml Powder for Suspension should not be used in the following situations:
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Hypersensitivity (allergy) to Cefuroxime or other cephalosporin antibiotics: Patients who have had a severe allergic reaction to cephalosporins or other beta-lactam antibiotics (penicillins) should avoid this medication.
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Severe allergic reactions to components: If there is a known allergy to any of the excipients in the product, it should not be used.
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History of anaphylaxis or severe allergic reactions to penicillin antibiotics: Cross-sensitivity may occur between penicillins and cephalosporins. Patients with a history of severe reactions to penicillins may be at higher risk for similar reactions to Cefuroxime Axetil.
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Severe renal impairment: In patients with very poor kidney function, dosage adjustments or an alternative antibiotic may be necessary, as Cefuroxime is eliminated via the kidneys.
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Newborns: Cefuroxime may not be suitable for neonates (newborns) unless prescribed by a doctor, especially in those with immature renal function.
Precautions:
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Renal impairment: In patients with renal impairment, dosing adjustments may be required, and the patient should be closely monitored.
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Pregnancy: Cefuroxime is generally considered safe during pregnancy, but it should only be used if clearly needed and prescribed by a doctor. It should be used with caution during the first trimester.
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Breastfeeding: Cefuroxime is excreted in breast milk in small amounts, and it is generally considered safe during breastfeeding, but a healthcare provider should be consulted.
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Gastrointestinal disorders: Use with caution in patients with a history of gastrointestinal diseases, such as colitis (inflammation of the colon).
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Drug interactions: Cefuroxime may interact with other medications, including antacids and probenecid (used for gout). Always inform your healthcare provider about any other medications you are taking.
Summary:
SQcef 250mg/5ml Powder for Suspension is a broad-spectrum antibiotic used to treat a variety of bacterial infections, including respiratory, urinary, skin, and soft tissue infections. It contains Cefuroxime Axetil, which is effective against many types of bacteria.
When using this medication, it is important to adhere to the prescribed dosages and to monitor for any adverse reactions. If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately. Always follow the healthcare provider's advice, especially if you have pre-existing conditions like renal impairment or allergies to antibiotics.
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