Chlorphenamine Maleate (Riphen) 2mg/5ml Syrup 60ml

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Product Description:

Riphen (Chlorphenamine Maleate 2mg/5ml) is an antihistamine used to relieve symptoms of allergic reactions. It comes in a syrup form, with 2mg of Chlorphenamine Maleate per 5ml of syrup, and is available in a 60ml bottle. Chlorphenamine Maleate is a first-generation H1-antihistamine that works by blocking the effects of histamine, a chemical released during allergic reactions, which causes symptoms like itching, swelling, and redness. This medication is often used to alleviate symptoms of hay fever, allergies, and other conditions related to histamine release.

• The syrup form of Riphen is suitable for both adults and children, offering ease of dosing and improved compliance.

• Riphen has sedative properties and may cause drowsiness in some individuals.

Indications:

Riphen (Chlorphenamine Maleate) syrup is primarily used to treat various allergic conditions and symptoms associated with histamine release, including:

1. Allergic Rhinitis: Symptoms such as sneezing, runny nose, itching, and nasal congestion caused by hay fever or other allergic triggers.

2. Conjunctivitis: Allergic reactions affecting the eyes, leading to itching, redness, and watering.

3. Urticaria: Hives or rash, causing itching and swelling on the skin.

4. Insect Bites and Stings: To relieve symptoms of itching and swelling caused by insect stings or bites.

5. Allergic reactions to foods, medications, or environmental allergens.

6. Common Cold Symptoms: As part of symptomatic relief for cold-related symptoms like sneezing and watery eyes.

7. Anaphylactic reactions (in adjunct to other treatments): To manage allergic responses, although it is not a first-line treatment for severe anaphylaxis.

Dosage:

Riphen (Chlorphenamine Maleate 2mg/5ml) syrup should be taken as prescribed by a healthcare provider. The usual doses are:

For Adults and Children Over 12 Years:

• Initial Dose: 10ml (4mg) of syrup every 4 to 6 hours as needed.

• Maximum Dose: 60ml per day (24mg), but this is typically not exceeded.

For Children (6 to 12 Years):

• Initial Dose: 5ml (2mg) of syrup every 4 to 6 hours as needed.

• Maximum Dose: 30ml per day (12mg).

For Children (2 to 6 Years):

• Initial Dose: 2.5ml (1mg) of syrup every 4 to 6 hours as needed.

• Maximum Dose: 15ml per day (6mg).

For Infants (Under 2 Years):

• The use of this medication in infants under 2 years old is not recommended unless directed by a healthcare professional. The dosage should be carefully calculated by a doctor.

Side Effects:

Although Riphen (Chlorphenamine Maleate) syrup is generally well-tolerated, it may cause some side effects. The common and serious side effects include:

Common Side Effects:

• Drowsiness or sedation: A typical effect of first-generation antihistamines, which may impair the ability to perform tasks requiring alertness (e.g., driving).

• Dry mouth: A common side effect of antihistamines.

• Dizziness or lightheadedness.

• Headache.

• Nausea or stomach upset.

• Blurred vision (less common).

• Fatigue or feeling unusually tired.

Serious Side Effects (Less Common):

• Allergic reactions: Signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing.

• Tachycardia (fast heart rate).

• Confusion or agitation (especially in children or the elderly).

• Urinary retention: Difficulty urinating or reduced urine flow.

• Severe dizziness or fainting.

• Convulsions: In rare cases, especially in overdose situations or sensitive individuals.

• Chest tightness or difficulty breathing: May indicate an allergic or serious reaction.

If you experience any serious side effects, seek medical attention immediately.

Contraindications:

Riphen (Chlorphenamine Maleate) syrup should not be used in certain individuals. Contraindications include:

1. Hypersensitivity or Allergy to Chlorphenamine Maleate or any of the excipients in the product. If you have had an allergic reaction to similar antihistamines in the past, you should avoid using this product.

2. Severe Liver or Kidney Dysfunction: Patients with significant liver or kidney disease should not take Riphen or should do so under strict medical supervision, as the drug may not be eliminated properly.

3. Neonates and Infants: Use in newborns and infants under 2 years of age is generally not recommended due to the potential for severe side effects and lack of safety data.

4. Breastfeeding: Chlorphenamine Maleate can pass into breast milk, so it should be used with caution or avoided if you are breastfeeding. Always consult a healthcare provider before using it while breastfeeding.

5. Acute Asthma: While not typically a direct contraindication, antihistamines like Riphen are not first-line treatments for acute asthma and should be avoided during acute bronchial asthma attacks.

6. Angle-Closure Glaucoma: Riphen can cause pupil dilation, which may increase the risk of angle-closure glaucoma in patients with this condition.

Precautions:

• Elderly Patients: Older adults are more likely to experience side effects like drowsiness, confusion, and urinary retention. Use Riphen with caution in elderly individuals, especially those with prostate problems or urinary issues.

• Alcohol: Alcohol can enhance the sedative effects of Riphen and should be avoided during treatment to prevent excessive drowsiness and potential impairment.

• Children: Riphen may cause excitement, restlessness, or agitation in some children, so it should be used with caution in pediatric patients.

• Operating Machinery: Due to the potential sedative effects, it is advised to avoid driving or operating heavy machinery while taking this medication until you know how it affects you.

• Pregnancy: While Chlorphenamine Maleate is categorized as a Category B drug during pregnancy, meaning it is not expected to harm the fetus, it should still be used only when the benefits outweigh the risks. Always consult with a healthcare provider before using during pregnancy.

Drug Interactions:

• Other Sedatives and CNS Depressants: Riphen can enhance the effects of other central nervous system depressants, including alcohol, sedatives, antidepressants, and antianxiety medications, leading to increased drowsiness or sedation.

• Monoamine Oxidase Inhibitors (MAOIs): Chlorphenamine Maleate should not be taken with MAO inhibitors due to the potential for severe hypertensive crises.

• Anticholinergic Drugs: Caution should be used when combining Riphen with other anticholinergic medications, as this may increase the risk of urinary retention, dry mouth, and confusion.

• Antacids: Antacids may alter the absorption of Riphen, especially if taken simultaneously. It is recommended to space out doses.

Summary:

Riphen (Chlorphenamine Maleate 2mg/5ml) is an antihistamine syrup used to treat allergic conditions such as hay fever, allergic rhinitis, urticaria, and insect bites. It works by blocking the effects of histamine to relieve symptoms like itching, sneezing, and runny nose.

• The usual dosage is 5ml (2mg) every 4-6 hours for children, and 10ml (4mg) every 4-6 hours for adults.

• Common side effects include drowsiness, dry mouth, and headache. Serious side effects can include severe allergic reactions, confusion, and seizures.

• Riphen should be avoided in neonates, infants under 2 years, and those with severe liver or kidney dysfunction.

• It should be used with caution in elderly individuals, and alcohol should be avoided during treatment.

As with all medications, it is important to follow the prescribed dosage and consult a healthcare provider if you have any concerns or experience side effects.