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Co Amoxiclav (Comxicla) 1g Film Coated Tablet 10's
Co Amoxiclav (Comxicla) 1g Film Coated Tablet 10's
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Description:
Used in adults and children to treat: middle ear and sinus infections. throat or lung respiratory tract infections. urinary tract infections.
Expiry: 01/2026
Product Description:
Co-Amoxiclav (Comxicla) 1g Film-Coated Tablets are a combination antibiotic medication containing Amoxicillin and Clavulanic Acid. This combination is commonly used to treat a wide range of bacterial infections. Amoxicillin is a penicillin-type antibiotic that works by inhibiting the growth of bacteria, while Clavulanic Acid is a beta-lactamase inhibitor that helps prevent certain bacteria from breaking down Amoxicillin, thereby enhancing its effectiveness.
Each tablet contains:
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Amoxicillin: 875 mg
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Clavulanic Acid: 125 mg
This combination provides 1g of the active ingredients per tablet. The product comes in a pack of 10 film-coated tablets, which are easy to swallow and designed to release the medication gradually for optimal absorption.
Key Features:
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Combination Antibiotic: Contains a blend of Amoxicillin and Clavulanic Acid, effective against a wide variety of bacterial infections.
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Film-Coated Tablets: The tablets are coated to make them easier to swallow and to protect the active ingredients from stomach acids.
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Effective Against Resistant Bacteria: The addition of Clavulanic Acid helps protect Amoxicillin from bacterial enzymes, allowing it to be effective against certain bacteria that are resistant to standard penicillin antibiotics.
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Commonly Used for Infections: It is commonly prescribed for respiratory infections, urinary tract infections, skin infections, and ear infections.
Indications:
Co-Amoxiclav (Comxicla) is indicated for the treatment of various bacterial infections, including:
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Respiratory Tract Infections:
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Pneumonia, bronchitis, sinusitis, and pharyngitis.
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Urinary Tract Infections:
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Infections of the bladder, kidneys, and urethra (e.g., cystitis, pyelonephritis).
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Skin and Soft Tissue Infections:
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Abscesses, cellulitis, infected wounds, and animal bites.
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Ear Infections:
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Otitis media (middle ear infections).
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Dental Infections:
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Tooth abscesses and gum infections.
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Infections in Immunocompromised Patients:
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Often prescribed in immunocompromised patients to prevent or treat infections due to its broad-spectrum activity.
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Bone and Joint Infections:
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Infections such as osteomyelitis.
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Dosage:
The typical dosage of Co-Amoxiclav (Comxicla) 1g Film-Coated Tablets is as follows:
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Adults:
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1 tablet (1g) every 12 hours (twice a day). The specific dosage may depend on the type and severity of the infection.
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Children:
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The dosage for children is generally based on their weight and the infection being treated. Co-Amoxiclav is usually prescribed in liquid form for children, but if a doctor deems the tablet form appropriate, the dosage should be carefully followed as directed by the healthcare provider.
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Note: This medication should be taken as prescribed, typically with food, to reduce the likelihood of gastrointestinal upset. If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not take two doses at the same time to make up for a missed dose.
Side Effects:
Co-Amoxiclav (Comxicla) is generally well-tolerated, but side effects may occur. Common and less common side effects include:
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Common Side Effects:
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Gastrointestinal discomfort: Nausea, diarrhea, abdominal pain, and vomiting.
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Headache.
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Skin rash or itching.
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Serious Side Effects:
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Allergic reactions: Swelling of the face, lips, tongue, or throat, difficulty breathing, which may indicate a severe allergic reaction (anaphylaxis).
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Liver problems: Symptoms like yellowing of the skin or eyes (jaundice), dark urine, or unusual fatigue.
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Severe diarrhea: Particularly if it is watery or bloody, which could indicate a serious gut infection (Clostridium difficile-associated diarrhea).
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Hematologic reactions: Unusual bruising or bleeding, pale skin, or symptoms of anemia.
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If any of these serious side effects occur, seek medical attention immediately.
Contraindications:
Co-Amoxiclav (Comxicla) should not be used in the following conditions:
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Allergy to Penicillin or Beta-lactams: If you have a known allergy to penicillin antibiotics, Amoxicillin, or any other beta-lactam antibiotics, you should not use this medication.
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Liver Disease: Patients with a history of jaundice or liver problems related to Amoxicillin/Clavulanate should avoid using this medication.
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Severe Renal Impairment: People with severe kidney dysfunction should use this drug cautiously and may require a dosage adjustment.
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Mononucleosis: Individuals with mononucleosis (often caused by the Epstein-Barr virus) should avoid taking Amoxicillin or Co-Amoxiclav due to an increased risk of developing a skin rash.
Warnings and Precautions:
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Antibiotic Resistance: Overuse or misuse of antibiotics can contribute to the development of antibiotic-resistant bacteria. Always complete the prescribed course, even if symptoms improve before finishing the medication.
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Gastrointestinal Issues: Co-Amoxiclav can sometimes cause gastrointestinal disturbances, including diarrhea. If severe diarrhea occurs, contact your healthcare provider.
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Liver Function Monitoring: For long-term use or in those with pre-existing liver conditions, liver function should be monitored periodically, as Clavulanic acid can affect liver enzymes.
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Kidney Function: Patients with renal impairment may require a dose adjustment.
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Superinfection: Long-term use of antibiotics can lead to secondary infections, such as yeast infections. Contact your healthcare provider if you develop symptoms of a secondary infection.
Pregnancy and Breastfeeding:
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Pregnancy: Co-Amoxiclav is classified as Category B by the FDA, meaning it is generally considered safe for use during pregnancy when prescribed by a healthcare provider. However, it should be used only when clearly needed and prescribed by a doctor.
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Breastfeeding: Co-Amoxiclav is excreted in breast milk in small amounts. It is generally considered safe for use during breastfeeding, but nursing mothers should consult their doctor before use to ensure it is the right choice for them.
Drug Interactions:
Co-Amoxiclav may interact with the following drugs:
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Probenecid: This medication may reduce the excretion of Amoxicillin, increasing the blood levels of the drug.
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Allopurinol: When taken together, Allopurinol may increase the likelihood of allergic skin reactions to Amoxicillin.
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Oral Contraceptives: While Co-Amoxiclav does not interfere significantly with oral contraceptives, there may be a slight reduction in effectiveness, so an alternative or backup form of contraception may be recommended during treatment.
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Anticoagulants (e.g., Warfarin): Co-Amoxiclav may increase the effects of anticoagulants, raising the risk of bleeding. If you are taking blood-thinning medications, monitor your INR levels closely.
Storage:
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Store Co-Amoxiclav (Comxicla) 1g Film-Coated Tablets in a cool, dry place away from direct sunlight.
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Keep the product in its original packaging and out of the reach of children.
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Do not use the medication past the expiration date printed on the packaging.
Conclusion:
Co-Amoxiclav (Comxicla) 1g Film-Coated Tablets is an effective antibiotic combination for treating a variety of bacterial infections. The inclusion of Clavulanic Acid helps protect Amoxicillin from bacterial resistance mechanisms, making it effective against a wider range of pathogens. As with all antibiotics, it is essential to follow the prescribed dosage and finish the full course of treatment to prevent the development of antibiotic resistance. Always consult with a healthcare provider before starting this medication, especially if you have underlying health conditions or are pregnant or breastfeeding.
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