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Bambang Pharmaceutical Depot Inc.

Eperisone HCI (Perispa) 50mg Suger Coated Tablet 30's

Eperisone HCI (Perispa) 50mg Suger Coated Tablet 30's

Regular price ₱1,385.00
Regular price ₱2,770.00 Sale price ₱1,385.00
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Product Description:

Eperisone Hydrochloride (Perispa) 50mg Sugar-Coated Tablets is a muscle relaxant used to treat various conditions involving muscle spasticity or muscle pain. Eperisone works by targeting the central nervous system (CNS) to help relieve muscle stiffness and spasm, while also reducing pain associated with such conditions. It has a centrally acting mechanism, helping to improve mobility and comfort. The product comes in a sugar-coated tablet form with each tablet containing 50mg of Eperisone Hydrochloride. The tablets are typically packaged in a 30-tablet bottle.


Indications:

Eperisone Hydrochloride (Perispa) is primarily used for the treatment of the following conditions:

  1. Muscle Spasms and Spasticity:

    • Eperisone is commonly used to relieve muscle spasms and stiffness, often associated with neurological disorders or musculoskeletal injuries.

  2. Musculoskeletal Disorders:

    • Used for conditions such as cervical spondylosis, lumbar spondylosis, muscle strains, or sprains to relieve muscle tension and pain.

  3. Pain Management in Musculoskeletal Diseases:

    • Helps to alleviate pain resulting from conditions that cause muscle tightness, including osteoarthritis and rheumatoid arthritis.

  4. Post-surgical Recovery:

    • May be used to manage muscle spasms and discomfort after certain surgeries, including orthopedic or spinal surgery.

  5. Other Neurological Disorders:

    • It is sometimes used in the management of neurological conditions like stroke, multiple sclerosis, or cerebral palsy that cause muscle stiffness and spasticity.


Dosage:

The dosage of Eperisone Hydrochloride (Perispa) depends on the specific condition being treated and the patient's response to the medication. Below are general guidelines:

For Adults:

  • Initial Dose: Typically, 50 mg (1 tablet), taken two to three times a day.

  • Maintenance Dose: The dose may be adjusted to 100 mg (2 tablets) taken twice a day depending on the severity of the condition and patient response.

For Elderly or Patients with Kidney/Liver Impairment:

  • A lower starting dose may be required in elderly patients or those with renal or hepatic dysfunction. This should be determined by the healthcare provider.

Administration:

  • Perispa should be taken with water after meals to minimize gastrointestinal irritation.

  • Always follow the specific instructions provided by your doctor for the correct dosage and duration of treatment.


Side Effects:

While Eperisone Hydrochloride (Perispa) is generally well-tolerated, some side effects may occur. These can range from mild to more serious, though not everyone will experience them.

Common Side Effects:

  • Dizziness or lightheadedness, especially when standing up quickly (due to its CNS effects).

  • Drowsiness or sedation (may affect alertness).

  • Headache.

  • Nausea or mild gastrointestinal upset.

  • Dry mouth.

Serious Side Effects (Rare):

  • Severe Allergic Reactions: Symptoms may include rash, itching, swelling, difficulty breathing, or tightness in the chest (anaphylaxis). Seek emergency medical attention if this occurs.

  • Hypotension (low blood pressure): May cause dizziness or fainting, especially if the medication is taken in conjunction with other antihypertensive drugs.

  • Liver Dysfunction: Although rare, symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or abdominal pain should be investigated.

  • Severe Weakness or Muscle Problems: Rarely, patients may experience severe weakness or muscle pain (myopathy), which may require discontinuation of the drug.

Other Effects:

  • Sleep disturbances or mild mood changes have been reported in some individuals.


Contraindications:

Eperisone Hydrochloride (Perispa) should not be used in the following situations:

  1. Hypersensitivity to Eperisone or any Component of the Product:

    • Contraindicated in individuals with a known allergy to Eperisone or any of the excipients in the tablet.

  2. Severe Liver or Kidney Impairment:

    • Not recommended for individuals with severe hepatic (liver) or renal (kidney) failure, as Eperisone is metabolized and excreted via these organs. The medication may accumulate in the body, leading to toxicity.

  3. Pregnancy:

    • Eperisone should be used with caution during pregnancy, especially during the first trimester, unless the potential benefits outweigh the risks. It is best to consult a doctor before using it during pregnancy.

  4. Breastfeeding:

    • Since it is not known whether Eperisone is excreted in breast milk, it should be used cautiously in breastfeeding women. Consult a healthcare provider before using this medication while nursing.


Precautions:

  • Dizziness or Drowsiness: Due to its CNS depressant effects, caution should be exercised when operating machinery or driving while using Eperisone. Patients should avoid activities that require full alertness until they understand how the medication affects them.

  • Drug Interactions: Eperisone may have interactions with other medications, especially those that have CNS depressant effects (e.g., benzodiazepines, opioids, antidepressants), as they may enhance the sedative effects of Eperisone.

  • Alcohol: Eperisone can enhance the sedative effects of alcohol, leading to increased drowsiness and impaired coordination. It's advisable to avoid alcohol while taking this medication.

  • Liver and Kidney Function: Regular monitoring of liver and kidney function is recommended in patients with underlying liver or kidney diseases, as the drug's clearance may be affected in these cases.


Drug Interactions:

Eperisone Hydrochloride (Perispa) may interact with the following drugs:

  1. CNS Depressants:

    • Co-administration with other sedatives, benzodiazepines, or opioids may increase drowsiness and sedation. Use with caution and under medical supervision.

  2. Antihypertensive Medications:

    • Due to the potential of Eperisone to cause hypotension (low blood pressure), its use should be monitored when taken alongside antihypertensive drugs.

  3. Alcohol:

    • Alcohol should be avoided while taking Eperisone, as it can enhance CNS depression, leading to severe drowsiness, dizziness, or even loss of consciousness.

  4. Muscle Relaxants:

    • Using Eperisone with other muscle relaxants may increase the risk of excessive muscle relaxation and further CNS depression.


Conclusion:

Eperisone Hydrochloride (Perispa) is a muscle relaxant used to relieve muscle spasms and stiffness due to various musculoskeletal and neurological conditions. While generally safe and effective, it can cause side effects such as dizziness, drowsiness, and gastrointestinal issues. It is contraindicated in people with severe liver or kidney disease and should be used cautiously during pregnancy and breastfeeding. Always follow the prescribed dosage and consult your healthcare provider if any serious side effects occur.

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