Gentamicin (Gentcare) 3mg/ml 0.3% W/V Opthalmic / Otic Solution 8ml

3mg/ml 0.3% W/V Opthalmic / Otic Solution

Here’s the detailed information for Gentamicin (Gentcare) 3mg/ml 0.3% W/V Ophthalmic/Otic Solution 8ml:

Product Description:

Gentamicin (Gentcare) is an ophthalmic/otic solution containing Gentamicin sulfate, a broad-spectrum aminoglycoside antibiotic, with a concentration of 3mg/ml (0.3% W/V). It comes in a 8ml bottle, designed for eye and ear infections. Gentamicin works by inhibiting the growth of bacteria by interfering with protein synthesis in the bacterial cells.

• For Ophthalmic Use (Eye): It treats bacterial infections of the eye, such as conjunctivitis (pink eye) or keratitis (inflammation of the cornea).

• For Otic Use (Ear): It is used for treating external ear infections like otitis externa (swimmer’s ear), and infections of the middle ear.

This solution is applied topically to the affected area (eye or ear) and is available over-the-counter or via prescription, depending on local regulations.

Indications:

Gentamicin (Gentcare) 3mg/ml Ophthalmic/Otic Solution is used for the treatment of bacterial infections in the eye and ear caused by susceptible organisms. These include:

Ophthalmic Indications (for Eye Infections):

1. Conjunctivitis: Inflammation or infection of the conjunctiva (the mucous membrane that covers the white part of the eyeball).

2. Keratitis: Inflammation of the cornea, usually caused by bacterial infection.

3. Blepharitis: Inflammation of the eyelid caused by bacteria.

4. Post-operative Eye Infections: After surgery, to prevent or treat bacterial infections.

Otic Indications (for Ear Infections):

1. Otitis Externa (Swimmer’s Ear): Infection of the outer ear canal caused by bacteria.

2. Otitis Media (Middle Ear Infections): Bacterial infection of the middle ear, although more common oral or systemic antibiotics are typically used for more severe cases.

3. Ear Canal Infections: For bacterial infections localized in the ear canal.

Dosage and Administration:

Gentamicin (Gentcare) 3mg/ml Ophthalmic/Otic Solution should be used according to the specific infection and the healthcare provider's recommendations. Below are general dosage guidelines.

For Ophthalmic Use (Eye Infection):

• Adults and Children:

  • 1-2 drops into the affected eye(s) every 4-6 hours for 7 to 10 days or as directed by the healthcare provider.

  • For severe infections, the dose may be increased to 1 drop every 1-2 hours during the first 24-48 hours, then reduced gradually.

For Otic Use (Ear Infection):

• Adults and Children:

  • For external ear infections (otitis externa):

    • 2-3 drops into the affected ear, 3-4 times a day.

    • Continue for about 7 to 10 days or as prescribed.

  • For middle ear infections (otitis media):

    • Typically, 1-2 drops in the ear 2-3 times a day or as prescribed by the healthcare provider.

Note: The solution should be instilled directly into the ear canal or eye, as per the specific infection type. Always wash hands thoroughly before and after using the medication to avoid contamination.

Side Effects:

While Gentamicin (Gentcare) is generally well-tolerated, it may cause some side effects, especially if used for prolonged periods or inappropriately.

Common Side Effects:

1. Ophthalmic Use (Eye):

   • Burning or stinging sensation in the eye.

   • Redness or mild irritation of the eye.

   • Dryness or increased tearing.

   • Blurred vision (usually temporary).

2. Otic Use (Ear):

   • Ear irritation or itching.

   • Mild discomfort in the ear.

   • Ear pain or fullness in the ear.

Serious but Rare Side Effects:

1. Ophthalmic Use:

   • Allergic reaction: Rash, swelling, or itching around the eyes or face.

   • Severe irritation or redness that doesn't go away.

   • Eye infections: Prolonged use may increase the risk of secondary eye infections, especially fungal infections.

2. Otic Use:

   • Severe ear pain or swelling.

   • Hearing loss or a feeling of fullness in the ear (especially with long-term use or high doses).

   • Allergic reactions: Redness, itching, or swelling of the ear or surrounding area.

If any of these serious side effects occur, discontinue the medication and seek medical attention immediately.

Contraindications:

Gentamicin (Gentcare) is contraindicated in the following conditions:

1. Hypersensitivity to Gentamicin or Aminoglycosides:

   • Gentamicin (Gentcare) should not be used by individuals with a known allergy to Gentamicin or other aminoglycoside antibiotics.

2. Ear Infections with Perforated Eardrum:

   • Gentamicin should not be used in cases of perforated eardrum (ruptured tympanic membrane) unless advised by a healthcare provider, as it may lead to hearing damage.

3. Ocular Herpes Simplex Virus Infection:

   • Avoid using Gentamicin (Gentcare) in individuals with ocular herpes simplex virus (HSV) infection, as it may exacerbate the infection.

Precautions:

• Superinfection: Prolonged use of Gentamicin (Gentcare) may lead to a superinfection (growth of non-susceptible organisms), including fungi. If signs of a secondary infection occur, discontinue the product and seek medical advice.

• Pregnancy and Breastfeeding:

  • Gentamicin should be used during pregnancy only if clearly needed. It is classified as a Category D drug for pregnancy, indicating a potential risk to the fetus. Consult a healthcare provider before use if pregnant or breastfeeding.

• Ocular Toxicity: Prolonged use of Gentamicin in the eyes may lead to ocular toxicity, including damage to the optic nerve and retina. Avoid prolonged use without medical supervision.

• Use with Caution in Children:

  • The use of Gentamicin in young children, especially in the eye, should be done under strict medical supervision to avoid toxicity.

• Do Not Touch the Dropper: To prevent contamination, do not allow the dropper tip to come in contact with any surface, including the eye, ear, or hands.

Summary:

Gentamicin (Gentcare) 3mg/ml 0.3% Ophthalmic/Otic Solution is a broad-spectrum antibiotic used for treating bacterial infections of the eye and ear, including conditions such as conjunctivitis, keratitis, and otitis externa.

• Dosage: For eye infections, 1-2 drops every 4-6 hours; for ear infections, 2-3 drops 3-4 times a day.

• Side Effects: May include eye irritation, ear discomfort, allergic reactions, and hearing loss (rare).

• Contraindications: Avoid use in individuals with allergy to Gentamicin or perforated eardrum.

Always follow the instructions provided by your healthcare provider and report any side effects or concerns promptly.