Ibuprofen ( Penfro) 200mg/5ml Suspension 60ml

Generic Name: Ibuprofen

Brand Name: PENFRO

Strength: 200mg / 5mL

Form: Suspension

Manufacturer: LifeSquare Laboratories, Inc.

Imported and Distributed by: ALMAN PHARMACEUTICALS, INC.

Classification: ANTI-INFLAMMATORY DRUG

Indication/Uses: 
Ibuprofen (Penfro) 200 mg/5 ml Suspension is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever.

Patients should consult their healthcare provider for personalized advice and report any adverse reactions promptly. Regular follow-ups may be necessary to monitor for potential side effects and ensure the medication is working effectively.

Product Description:

Ibuprofen (Penfro) 200mg/5mL Suspension 60mL is an oral liquid suspension containing 200 mg of ibuprofen per 5 mL. Ibuprofen is a widely used nonsteroidal anti-inflammatory drug (NSAID) known for its analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) properties. This formulation is specifically designed for individuals who have difficulty swallowing tablets or prefer a liquid form of medication. The syrup is commonly used to manage mild to moderate pain, reduce inflammation, and lower fever in both children and adults.

Indications:

Ibuprofen (Penfro) Suspension is indicated for:

• Pain Relief: To relieve mild to moderate pain, such as headaches, toothaches, muscle pain, menstrual cramps, or pain associated with injury or surgery.

• Fever Reduction: To lower fever caused by infections or other conditions.

• Inflammatory Conditions: For the treatment of inflammation caused by conditions like arthritis, bursitis, or tendinitis.

• Rheumatic Conditions: To treat conditions like rheumatoid arthritis or osteoarthritis in both adults and children (as directed by a healthcare provider).

• Post-operative Pain: To manage pain following surgery or medical procedures.

Dosages:

The dosage of Ibuprofen (Penfro) Suspension depends on the age, weight, and medical condition of the patient. It is essential to follow the prescribed dose to avoid side effects, particularly when using ibuprofen for children.

• Adults:

  • The typical dose for pain and inflammation is 10-15 mL (400-600 mg of ibuprofen) every 4-6 hours as needed.

  • Do not exceed 1200 mg (30 mL) per day without medical supervision.

• Children (6 months to 12 years):

  • Children aged 6 months–2 years: 2.5-5 mL (100-200 mg of ibuprofen) every 6-8 hours, as needed.

  • Children aged 2–5 years: 5-7.5 mL (200-300 mg of ibuprofen) every 6-8 hours.

  • Children aged 6-12 years: 7.5-10 mL (300-400 mg of ibuprofen) every 6-8 hours.

  • The maximum dose for children should not exceed 40 mg per kg of body weight in a 24-hour period.

• Infants (6 months and younger):

  • Ibuprofen should not be used in infants younger than 6 months unless prescribed by a healthcare provider. Always consult with a pediatrician before giving ibuprofen to an infant.

Note: It is important to measure the suspension carefully using the provided dosing spoon or dropper to avoid incorrect dosing.

Side Effects:

Common side effects of Ibuprofen (Penfro) Suspension may include:

• Gastrointestinal discomfort: Upset stomach, nausea, or vomiting, which are common with NSAIDs.

• Indigestion or heartburn: Some individuals may experience discomfort in the stomach after taking ibuprofen.

• Diarrhea or constipation: Digestive changes can occur, although these are less common.

• Headache: Some individuals may experience a mild headache as a side effect.

Serious side effects are less common but can include:

• Gastrointestinal bleeding or ulcers: Prolonged use or high doses of ibuprofen may cause damage to the stomach lining, leading to ulcers or bleeding.

• Kidney damage: NSAIDs like ibuprofen can affect kidney function, especially when used in high doses or over long periods.

• Severe allergic reactions: Signs include swelling of the face, lips, tongue, or throat, difficulty breathing, or skin rash.

• Liver damage: Although rare, ibuprofen can affect liver function, leading to jaundice or other liver-related symptoms.

• High blood pressure: Prolonged use may contribute to increased blood pressure or exacerbate existing hypertension.

If any of the following serious side effects occur, seek medical attention immediately:

• Severe allergic reactions: Difficulty breathing, swelling of the face or throat, rash, or hives.

• Signs of gastrointestinal bleeding: Vomiting blood, black or tarry stools, or severe abdominal pain.

• Kidney problems: Reduced urine output, swelling of the legs or ankles, or fatigue.

• Liver problems: Yellowing of the skin or eyes, dark urine, or abdominal pain.

Contraindications:

Ibuprofen (Penfro) Suspension should not be used in the following conditions:

• Hypersensitivity: If the patient is allergic to ibuprofen, other NSAIDs, or any of the ingredients in the suspension, it should be avoided.

• Active Peptic Ulcer Disease: Ibuprofen can irritate the stomach lining and exacerbate peptic ulcers or gastrointestinal bleeding.

• Gastrointestinal Bleeding or Disorders: If the patient has a history of gastrointestinal bleeding, inflammatory bowel disease (e.g., Crohn’s disease or ulcerative colitis), or other gastrointestinal disorders, ibuprofen should be avoided.

• Severe Heart Disease: People with severe heart conditions, such as heart failure or uncontrolled hypertension, should avoid NSAIDs, as they may exacerbate cardiovascular problems.

• Severe Kidney or Liver Disease: Ibuprofen is contraindicated in individuals with severe renal (kidney) or hepatic (liver) impairment.

• Third Trimester of Pregnancy: Ibuprofen should not be used during the third trimester of pregnancy, as it may harm the developing fetus (especially the cardiovascular system).

Warnings and Precautions:

• Kidney and Liver Function: Ibuprofen should be used cautiously in patients with a history of kidney or liver disease, as it can exacerbate kidney damage or liver dysfunction. Regular monitoring may be required for long-term use.

• Heart Disease: Prolonged use of ibuprofen may increase the risk of heart attack or stroke, especially in patients with existing heart conditions or high blood pressure. Use the lowest effective dose for the shortest duration possible.

• Pregnancy and Breastfeeding: Ibuprofen should be avoided during the third trimester of pregnancy due to potential harm to the fetus. It is generally considered safe during the first and second trimesters when used in low doses and for short periods, but a healthcare provider should be consulted. It is excreted in breast milk, so breastfeeding mothers should consult a doctor before using ibuprofen.

• Gastrointestinal Risk: Individuals with a history of gastrointestinal disorders, such as ulcers or inflammatory bowel disease, should use ibuprofen with caution, as it can cause or worsen gastrointestinal bleeding.

• Alcohol: Avoid drinking alcohol while using ibuprofen, as this can increase the risk of stomach bleeding and liver damage.

Conclusion:

Ibuprofen (Penfro) 200mg/5mL Suspension 60mL is a liquid formulation of ibuprofen used to manage pain, inflammation, and fever. It is particularly useful for individuals who have difficulty swallowing tablets, such as children or the elderly. The syrup provides a convenient and effective way to alleviate various types of pain and reduce fever. As with any medication, it is essential to follow the recommended dosage and be aware of the potential side effects and contraindications, especially in individuals with pre-existing health conditions. Always consult with a healthcare provider before starting or continuing treatment with ibuprofen, especially for long-term use or in vulnerable populations like children and pregnant women.