Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet 100's

Certainly! Here is the detailed information for Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet 100's:

Product Description:

Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet 100's is a specialized nutritional supplement designed for individuals with chronic kidney disease (CKD) or those who require dietary support for kidney function. This supplement combines ketoanalogues of essential amino acids and essential amino acids (EAAs) to help maintain protein balance while minimizing the strain on the kidneys.

• Ketoanalogues are compounds that are structurally similar to amino acids but lack a specific side-chain, making them less metabolically demanding. When taken in place of regular amino acids, they reduce the production of nitrogenous waste products, which are harmful to individuals with impaired kidney function.

• Essential Amino Acids (EAAs) are the building blocks of proteins that the body cannot produce on its own and must obtain from the diet. EAAs are vital for maintaining muscle mass, tissue repair, immune function, and many other physiological processes.

The combination of ketoanalogues and essential amino acids in Globisaph helps to improve protein synthesis, preserve lean body mass, and support overall health in individuals with CKD, while reducing the load on the kidneys.

Indications:

Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet is indicated for:

• Chronic Kidney Disease (CKD): Particularly in individuals with stage 2 to stage 4 CKD to help manage protein intake, support muscle mass, and reduce the risk of malnutrition and uremic toxicity.

• Renal Replacement Therapy: For patients undergoing dialysis or other forms of renal replacement therapy to help maintain nutritional status and minimize protein breakdown.

• Protein-Energy Wasting: To address protein-energy wasting, a condition common in kidney disease where the body loses lean muscle mass, often due to inadequate protein intake or poor protein utilization.

• Pre-dialysis: As a dietary supplement for individuals with reduced kidney function, who may need assistance in managing their protein intake before requiring dialysis.

• Malnutrition Prevention: To prevent or treat malnutrition in individuals with kidney disease by providing high-quality protein in a form that is less taxing on the kidneys.

Dosage and Administration:

The recommended dosage of Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet is:

• Adults:

  • Take 1 tablet 3 times daily with meals or as directed by a healthcare provider. This dosage helps provide the necessary balance of amino acids while minimizing the load on the kidneys.

• Children:

  • The use of this product in children should be determined by a healthcare provider based on individual needs.

Administration:

• Swallow the tablet whole with a glass of water.

• Do not crush or chew the tablet.

Side Effects:

Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet is generally well-tolerated when taken as directed. However, some individuals may experience side effects, particularly when first starting the supplement or if taken in higher-than-recommended doses:

• Gastrointestinal Distress: Some individuals may experience mild gastrointestinal discomfort such as bloating, nausea, or mild abdominal pain, particularly if the tablets are taken on an empty stomach.

• Allergic Reactions: In rare cases, individuals may experience allergic reactions, such as itching, rash, or swelling. If severe reactions such as difficulty breathing occur, immediate medical attention should be sought.

• Imbalance of Amino Acids: If taken in excessive amounts, there may be an imbalance in amino acid levels in the body, leading to metabolic disturbances. Always follow the recommended dosage.

• Hyperkalemia: Since this supplement contains amino acids that play a role in electrolyte balance, excessive use may lead to elevated potassium levels, especially in individuals with impaired kidney function.

Side effects are rare and typically mild. If you experience any severe or persistent reactions, it is important to discontinue use and consult a healthcare provider.

Contraindications:

Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet should be avoided or used with caution in the following conditions:

• Hypersensitivity: Individuals who are allergic to any of the ingredients in the product, including ketoanalogues or essential amino acids, should avoid using this supplement.

• Severe Kidney Dysfunction: Individuals with end-stage renal disease (ESRD) who are not receiving dialysis may require more specialized nutritional management. This product should only be used under the supervision of a healthcare provider in such cases.

• Electrolyte Imbalance: If you have any condition that affects electrolyte balance (such as hyperkalemia, hyponatremia), you should consult a healthcare provider before using this product, as amino acid supplementation may influence electrolyte levels.

• Pregnancy and Breastfeeding: The safety of Ketoanalogues + Essential Amino Acids (Globisaph) during pregnancy and breastfeeding has not been well-established. Consult a healthcare provider before use if pregnant or breastfeeding.

• Liver Disorders: While the primary concern with kidney disease is the metabolic load, individuals with severe liver disease should consult a healthcare provider before starting this product, as it may further stress liver function.

• Acute Kidney Injury (AKI): This product is not recommended for individuals with acute kidney injury unless specifically prescribed by a healthcare provider, as the body's ability to process and use amino acids may be impaired during acute kidney events.

Storage:

• Storage Conditions:

  • Store the tablets in a cool, dry place, away from direct sunlight and moisture.

  • Keep the bottle tightly closed when not in use.

  • Store at room temperature (20°C–25°C).

• Shelf Life:

  • Check the expiration date on the packaging. The shelf life of this product is generally 2-3 years when stored correctly.

Packaging:

Ketoanalogues + Essential Amino Acids (Globisaph) typically comes in a bottle containing 100 film-coated tablets. The size of the packaging is designed to last for approximately 1 month if the recommended dosage of 3 tablets per day is followed.

Conclusion:

Ketoanalogues + Essential Amino Acids (Globisaph) 630mg Film Coated Tablet 100's is a specialized supplement designed to support individuals with chronic kidney disease, protein-energy wasting, or those undergoing renal replacement therapy. It provides a balanced formula of ketoanalogues and essential amino acids, which help maintain muscle mass, reduce the metabolic burden on the kidneys, and prevent protein malnutrition. This product is beneficial for improving nutritional status and supporting kidney health.

As with any supplement, it is important to follow the recommended dosage and consult a healthcare provider, especially for individuals with severe kidney dysfunction or other underlying health conditions.