Ketoconazole Clobetasole Propionate (BL) 10mg/500mcg per Gram Antifungal Cream 7g

Here's a detailed overview of Ketoconazole Clobetasole Propionate (BL) 10mg/500mcg per Gram Antifungal Cream 7g:

Product Description

Ketoconazole Clobetasole Propionate (BL) 10mg/500mcg per Gram Antifungal Cream is a combination topical cream containing Ketoconazole (10mg per gram), an antifungal agent, and Clobetasol Propionate (500mcg per gram), a potent corticosteroid. This combination therapy is designed to treat fungal skin infections that also involve inflammation or irritation, offering dual action to fight infection and reduce inflammation.

• Formulation: Cream, suitable for topical application on the skin.

• Concentration:

  • Ketoconazole: 10mg per gram (antifungal agent).

  • Clobetasol Propionate: 500mcg per gram (potent anti-inflammatory corticosteroid).

• Pack Size: 7g, an ideal size for treating localized fungal infections with inflammation.

• Action:

  • Ketoconazole is an antifungal agent that inhibits the growth of fungi by interfering with the synthesis of ergosterol, an essential component of fungal cell membranes.

  • Clobetasol Propionate is a corticosteroid that reduces inflammation, redness, and swelling, providing relief from itching and discomfort associated with inflammatory skin conditions.

This combination is especially useful for treating skin conditions that involve both fungal infections and significant inflammation.

Indications

Ketoconazole Clobetasole Propionate (BL) Antifungal Cream is indicated for the treatment of:

• Fungal Skin Infections with Inflammation: This cream is primarily used for treating skin conditions caused by fungal infections where there is significant redness, swelling, or itching.

• Tinea Corporis (Ringworm): A fungal infection that affects the body, particularly on the arms, legs, or torso.

• Tinea Cruris (Jock Itch): Fungal infection in the groin area, often accompanied by itching and inflammation.

• Tinea Pedis (Athlete’s Foot): Fungal infection of the feet, typically between the toes, that can be complicated by inflammation and itching.

• Seborrheic Dermatitis: A fungal-related skin condition that causes red, flaky, and inflamed patches, commonly on the scalp, face, and upper body.

• Other Inflammatory Fungal Infections: Any other fungal infection with associated inflammation or severe symptoms that require both antifungal and anti-inflammatory treatment.

Dosages

The recommended dosage for Ketoconazole Clobetasole Propionate (BL) 10mg/500mcg per Gram Antifungal Cream is:

• Adults and Children (over 12 years):

  • Apply a thin layer of cream to the affected area once or twice a day, depending on the severity of the condition.

  • Gently rub the cream into the affected area after cleaning and drying the skin.

  • Duration of treatment varies depending on the condition:

    • For ringworm, jock itch, or athlete's foot, treatment typically lasts 2-4 weeks.

    • For conditions like seborrheic dermatitis, a typical treatment duration is 2-3 weeks.

• Children under 12 years: This medication should only be used under the supervision of a healthcare provider for children under 12 years, as prolonged use of corticosteroids in children can have adverse effects.

Note: Do not use for more than 4 weeks without consulting a healthcare provider. Prolonged use of corticosteroids may cause side effects, especially in areas with thinner skin.

Side Effects

Ketoconazole Clobetasole Propionate (BL) Antifungal Cream may cause some side effects, though not everyone will experience them. Common and serious side effects may include:

• Local Skin Irritation: Redness, burning, stinging, or itching at the site of application.

• Skin Dryness: Prolonged use may cause the skin to become dry or cracked.

• Thinning of the Skin: Chronic use of corticosteroids like Clobetasol can lead to thinning of the skin, which increases the risk of skin tears or bruising.

• Stretch Marks: Use of corticosteroids, especially over long periods, can cause stretch marks.

• Contact Dermatitis: Rare allergic reactions such as rash, swelling, or hives at the application site.

• Hypopigmentation: Lightening of the skin or changes in skin color in the treated area.

• Systemic Absorption (with prolonged use): If the cream is used on large areas or for extended periods, there may be a risk of systemic absorption, potentially leading to side effects like:

  • Cushing’s Syndrome (due to excessive corticosteroid absorption)

  • Hyperglycemia (elevated blood sugar levels)

  • Adrenal Suppression (inhibition of normal adrenal gland function)

If you experience severe side effects such as severe skin reactions, allergic reactions, or worsening of the condition, discontinue use and consult a healthcare provider immediately.

Contraindications

Ketoconazole Clobetasole Propionate (BL) Antifungal Cream should be avoided in the following situations:

• Hypersensitivity to Ketoconazole, Clobetasol Propionate, or Any of the Ingredients: Do not use if you have an allergy or hypersensitivity to any component of the cream.

• Viral Skin Infections: This product is contraindicated in cases of viral infections such as herpes simplex, chickenpox, or shingles, as the use of corticosteroids can worsen these conditions.

• Tuberculosis: Do not use in areas of the skin infected with tuberculosis.

• Open or Weeping Wounds: The corticosteroid component of this cream may slow down the healing process, so it should not be applied to large or deep open wounds.

• Systemic Fungal Infections: This product is for topical use only and should not be used in individuals with systemic fungal infections.

• Children Under 12 Years: Use with caution in children under 12 years old, as long-term use of corticosteroids can affect growth and development.

Caution:

• Pregnancy and Breastfeeding: The safety of using this medication during pregnancy or while breastfeeding has not been fully established. Use only if the potential benefit justifies the potential risk to the fetus or infant, and consult a healthcare provider.

• Prolonged Use: Avoid long-term use on large areas of the body or for prolonged periods to minimize the risk of systemic side effects related to corticosteroid absorption.

Additional Notes

• Application Area: Avoid applying the cream on areas of skin near the eyes or mucous membranes (e.g., inside the mouth, nose, or genitals), as it may cause irritation.

• Avoid Occlusive Dressings: Do not cover the treated area with tight bandages or occlusive dressings unless instructed by a healthcare provider, as this can increase the absorption of the corticosteroid and increase the risk of systemic side effects.

• Avoid Overuse: Overuse or misuse of corticosteroid-containing products can lead to unwanted side effects such as skin thinning, delayed wound healing, and systemic effects due to the absorption of corticosteroids.

Always follow the instructions provided by your healthcare provider or those on the label. If you have any concerns or experience any adverse effects, contact a healthcare provider immediately for advice.