Lidocaine Hydrochloride (Litaine) 20mg/ml (400mg/20ml) Solution for Injection 20ml x 10 Vials

20mg/ml (400mg/20ml) Solution for Injection 20ml

Here's a detailed overview of Lidocaine Hydrochloride (Litaine) 20mg/ml (400mg/20ml) Solution for Injection 20ml x 10 Vials:

Product Description

Lidocaine Hydrochloride (Litaine) 20mg/ml (400mg/20ml) Solution for Injection is a local anesthetic used for providing temporary numbing and pain relief during medical procedures. The product comes in vials containing 20 ml of solution, with a concentration of 20 mg/ml of lidocaine hydrochloride. Each vial contains 400 mg of lidocaine hydrochloride.

• Formulation: Lidocaine Hydrochloride in solution form, designed for injection.

• Concentration: 20 mg/ml (400 mg per 20 ml vial).

• Packaging: 10 vials per pack, suitable for use in both hospital settings and outpatient procedures.

• Action: Lidocaine works by blocking nerve signals in the body, providing localized anesthesia to prevent pain during surgical, diagnostic, or other minor medical procedures.

Litaine is a potent and widely used anesthetic solution for injections, often used for both surface (topical) and local anesthesia during a variety of minor surgical and diagnostic procedures.

Indications

Lidocaine Hydrochloride (Litaine) is used for the following purposes:

• Local Anesthesia: For local anesthesia during minor surgical or diagnostic procedures, such as dental work, minor skin surgeries, or tissue biopsies.

• Regional Anesthesia: For nerve block anesthesia to numb larger regions of the body for certain procedures like epidurals or peripheral nerve blocks.

• Pain Relief: Used in the management of acute pain, particularly in the form of nerve blocks or local injections.

• Emergency Use: Lidocaine can be used in emergency settings for certain pain management situations or for local numbing before more extensive procedures.

• Arrhythmia: Lidocaine is sometimes used in the emergency management of certain types of arrhythmias (irregular heartbeats), although this may depend on the specific formulation and medical protocol.

Dosages

The dosage of Lidocaine Hydrochloride (Litaine) depends on the nature of the procedure and the patient's individual factors such as age, weight, and medical condition. The typical dosing guidelines are as follows:

• For Local Anesthesia:

  • Adults: A typical dose is between 50 to 100 mg (2.5 to 5 ml of the 20 mg/ml solution) for minor procedures. The exact dosage will vary based on the size of the area being anesthetized and the duration of the procedure.

  • Maximum Dose: The total dose should not exceed 300 mg in adults for any single procedure.

  • For Nerve Blocks or Epidural: The dose for regional anesthesia can be adjusted based on the procedure's needs, typically ranging from 5 ml to 10 ml of the solution (100 mg to 200 mg).

• For Pediatric Use:

  • The dose in children is lower and should be determined based on body weight. Generally, a safe dose range is 3 to 5 mg/kg of body weight.

• For Cardiac Arrhythmias:

  • Initial Dose: 50 to 100 mg (2.5 to 5 ml of the 20 mg/ml solution) via slow IV injection. Additional doses may be administered based on clinical response.

Note: Doses may need to be adjusted based on the patient's response and condition. Always consult a healthcare provider to determine the correct dosage for individual patients.

Side Effects

While Lidocaine Hydrochloride (Litaine) is generally well-tolerated, some potential side effects may include:

• Common Side Effects:

  • Dizziness or Lightheadedness: Especially if too much lidocaine is used or if it is injected too quickly.

  • Nausea or Vomiting: Can occur in some patients as a reaction to the medication.

  • Skin Rash: In rare cases, patients may develop a rash or irritation at the injection site.

  • Headache: Some patients report headaches after receiving a lidocaine injection.

• Serious Side Effects:

  • Allergic Reactions: Rarely, patients may experience allergic reactions, including swelling, itching, or trouble breathing. This requires immediate medical attention.

  • Cardiovascular Effects: Overdose or rapid injection can lead to bradycardia (slow heart rate), hypotension (low blood pressure), or arrhythmias.

  • Central Nervous System Effects: High doses or accidental intravascular injection can cause seizures, confusion, tinnitus (ringing in the ears), or vision disturbances.

  • Respiratory Depression: If overdosed, lidocaine can cause difficulty breathing or a decreased respiratory rate.

  • Methemoglobinemia: A rare but serious condition that reduces the ability of blood to carry oxygen, which may occur with high doses.

If any of these serious side effects occur, immediate medical attention is necessary.

Contraindications

Lidocaine Hydrochloride (Litaine) should not be used in the following conditions:

• Hypersensitivity to Lidocaine: Patients with known hypersensitivity to lidocaine or any of the components of the formulation should not use this product.

• Severe Heart Block: Lidocaine should be avoided in patients with severe heart block unless they have a functioning pacemaker, as it can exacerbate conduction disturbances.

• Severe Liver Disease: Lidocaine is metabolized by the liver, so patients with severe liver impairment may have difficulty clearing the drug, which can increase the risk of toxicity.

• Cardiac Arrhythmias: Caution is required in patients with arrhythmias, as lidocaine can affect heart rhythms.

• Pregnancy: Lidocaine should be used in pregnancy only if clearly needed, and the potential benefits must outweigh the risks. Always consult a healthcare provider.

• Breastfeeding: Lidocaine passes into breast milk, so caution is advised for nursing mothers. It is typically considered safe for short-term use, but prolonged use or high doses should be avoided.

• Known Allergies: Avoid if allergic to other amide-type anesthetics (e.g., bupivacaine, mepivacaine).

Precautions

• Renal Impairment: Caution should be exercised in patients with kidney impairment, as lidocaine is excreted via the kidneys.

• Electrolyte Imbalance: Patients with imbalances in potassium or calcium should be monitored, as these can increase the risk of cardiac effects.

• Geriatric Use: Elderly patients may require lower doses of lidocaine due to reduced metabolic clearance and increased sensitivity to side effects.

• Overdose: Always be aware of the signs of lidocaine overdose, which can include dizziness, tinnitus, seizures, and respiratory depression. In case of overdose, discontinue the medication immediately and seek emergency medical care.

Additional Notes

• Injection Site: Care should be taken to avoid injecting into blood vessels, as this can lead to systemic toxicity. Always ensure proper technique.

• Storage: Store Lidocaine Hydrochloride (Litaine) at room temperature, away from moisture and heat. Protect from freezing.

Conclusion

Lidocaine Hydrochloride (Litaine) 20mg/ml (400mg/20ml) Solution for Injection is an effective and commonly used local anesthetic for a wide range of medical procedures. It provides reliable pain relief during surgeries, diagnostic procedures, and for certain emergency situations. However, like all medications, it should be used carefully, especially in patients with pre-existing medical conditions or those at risk of side effects. Always follow the recommended dosage and consult a healthcare provider before use to ensure safety.