Loperamide (Vexil) 2mg Capsule 100's

Here's a detailed overview of Loperamide (Vexil) 2mg Capsule 100's:

Product Description:

Loperamide (Vexil) 2mg Capsules contain Loperamide hydrochloride, which is an anti-diarrheal medication. It works by slowing down the movement of the muscles in the gut, thereby reducing the frequency of bowel movements and helping to manage the symptoms of diarrhea. Loperamide is commonly used to treat both acute and chronic diarrhea and is often used for traveler's diarrhea, as well as in conditions such as irritable bowel syndrome (IBS). The 100-count capsule format makes it convenient for long-term or bulk use, under medical supervision.

Indications:

Loperamide (Vexil) is indicated for the treatment of:

• Acute diarrhea: Used to reduce the frequency of stools and provide relief from symptoms.

• Chronic diarrhea: Often used in conditions like irritable bowel syndrome (IBS), where diarrhea is a dominant symptom.

• Traveler's diarrhea: Helps control diarrhea caused by bacterial infections while traveling, though it is not intended to treat the underlying infection.

• Post-surgical diarrhea: Can be used in certain cases where bowel movements need to be controlled after intestinal surgery.

Dosage:

The recommended dosage for Loperamide (Vexil) 2mg Capsules is as follows:

• For Acute Diarrhea:

  • Adults: Initial dose of 4mg (2 capsules) orally, followed by 2mg (1 capsule) after each loose stool. The maximum daily dose should not exceed 8mg (4 capsules) in a 24-hour period.

  • Children (over 6 years old): 2mg (1 capsule) after the first loose stool, then 2mg after each subsequent loose stool, up to a maximum of 4 doses (8mg) in 24 hours.

• For Chronic Diarrhea:

  • The dosage may vary depending on the severity of symptoms, but typically the starting dose is 4mg daily, which can be adjusted based on response.

  • Adults: The maximum dosage for chronic diarrhea is typically 16mg (8 capsules) per day, but should be adjusted according to the individual’s response and doctor’s advice.

Side Effects:

While Loperamide (Vexil) is generally well tolerated, some individuals may experience side effects. Common side effects include:

• Constipation or discomfort in the abdomen (e.g., bloating, cramps).

• Dizziness or drowsiness.

• Dry mouth.

• Nausea or vomiting.

Rare but serious side effects may include:

• Severe abdominal pain or distension, which could indicate a serious condition.

• Toxic megacolon (a rare but serious complication often seen in people with inflammatory bowel disease, such as ulcerative colitis).

• Cardiac issues, including abnormal heart rhythms (in rare cases, especially at high doses).

• Severe allergic reactions: Rash, swelling of the face or throat, difficulty breathing (anaphylaxis).

Note: If any of the serious side effects occur, discontinue use and seek immediate medical attention.

Contraindications:

Loperamide (Vexil) should not be used in the following cases:

• Hypersensitivity to Loperamide or any of the other ingredients in the product.

• Acute dysentery (diarrhea with blood and fever), as loperamide may worsen the condition.

• Infectious diarrhea caused by certain bacteria (e.g., Salmonella, Shigella) or Clostridium difficile, as it may slow the elimination of the infection.

• Pediatric use in children under 6 years old: Safety and effectiveness have not been established for this age group.

• Severe liver disease: Patients with liver impairment may be at higher risk for side effects due to slower drug metabolism.

• Acute abdominal conditions: Loperamide should not be used in cases of acute abdominal conditions like intestinal obstruction or acute inflammatory bowel diseases (e.g., ulcerative colitis).

Precautionary Use:

• Pregnancy and breastfeeding: Loperamide should be used during pregnancy only if clearly needed and prescribed by a healthcare provider. It is generally considered safe for short-term use while breastfeeding, but caution is advised.

• Children (6 years and older): Use only under the supervision of a healthcare provider.

Note: Always consult a healthcare professional before starting Loperamide (Vexil), particularly if there are pre-existing medical conditions or concerns regarding other medications.