Classification: ANGIOTENSIN II RECEPTOR ANTAGONIST
Indication/Uses:
Hypertension (High Blood Pressure):
Used to treat high blood pressure, helping to lower the risk of stroke and heart attack.
Diabetic Nephropathy:
Used to treat kidney disease in patients with type 2 diabetes and a history of hypertension.
Heart Failure:
Sometimes used in the treatment of heart failure, though this is an off-label use in some regions.
Left Ventricular Hypertrophy:
Used to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, a condition where the muscle wall of the heart's left pumping chamber thickens.
Uses:
Losartan works by blocking the action of angiotensin II, a chemical in your body that causes blood vessels to tighten and narrow. By blocking this action, Losartan helps to:
Relax Blood Vessels:
This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Protect Kidneys:
Especially in patients with type 2 diabetes and hypertension.
Prevent Strokes:
Particularly in hypertensive patients with left ventricular hypertrophy.
Dosage and Administration:
Dosage:
The typical starting dose for hypertension is 50mg once daily.
The dose may be increased to 100mg once daily based on blood pressure response.
For nephropathy in type 2 diabetic patients, the usual starting dose is 50mg once daily, increased to 100mg once daily based on blood pressure response.
Administration:
Losartan can be taken with or without food.
It is important to take it at the same time each day to maintain an even level in your bloodstream.
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