Mefenamic Acid (Infamix) 50mg/5ml Suspension is used for the relief of pain and inflammation, particularly in pediatric patients or individuals who have difficulty swallowing tablets or capsules. Here are the indications and uses:
Indications and Uses
Pain Relief:
Mild to Moderate Pain: Effective for relieving various types of pain, including headaches, toothaches, menstrual cramps, and musculoskeletal pain.
Menstrual Pain:
Dysmenorrhea: Commonly used to relieve pain associated with menstrual cramps.
Fever Reduction:
Antipyretic: Can be used to reduce fever, although it is not the primary indication.
Mechanism of Action
NSAID: Mefenamic Acid inhibits the production of prostaglandins by blocking the cyclooxygenase (COX) enzymes (COX-1 and COX-2). Prostaglandins are chemicals in the body that promote inflammation, pain, and fever. By reducing prostaglandin levels, Mefenamic Acid helps decrease these symptoms.
Dosage and Administration
Dosage:
Adults and Children Over 12 Years: The usual dose is 5-10ml (50-100mg) of suspension every 6-8 hours as needed. The maximum daily dose should not exceed 1.5g (150ml of suspension).
Children (6-12 Years): The dosage should be adjusted based on weight and the specific condition being treated. Typically, 5ml (50mg) every 6-8 hours as needed. Consult a healthcare provider for precise dosing.
Administration:
Oral: Shake the bottle well before each use. Use the provided measuring spoon or dropper to ensure accurate dosing. Administer the suspension with or without food.
Instructions for Use
Regular Use:
Adhere to the prescribed dosage and schedule. Do not exceed the recommended dose or duration of use without consulting a healthcare provider.
Missed Dose:
If a dose is missed, take it as soon as possible. If it is close to the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses.
Precautions
Allergic Reactions: Ensure there are no known allergies to Mefenamic Acid or other NSAIDs.
Gastrointestinal Issues: Use with caution in individuals with a history of gastrointestinal problems, such as ulcers or bleeding.
Kidney and Liver Function: Monitor kidney and liver function, especially with prolonged use.
Pregnancy and Breastfeeding: Consult a healthcare provider before using Mefenamic Acid during pregnancy or breastfeeding.
Side Effects
Common: Gastrointestinal symptoms such as nausea, vomiting, diarrhea, or abdominal pain. The liquid form may have a taste that some may find unpleasant.
Serious: Rare but may include severe allergic reactions, gastrointestinal bleeding, liver or kidney dysfunction, or cardiovascular issues. Seek medical attention if serious side effects occur.
Storage
Storage: Store the suspension in a cool, dry place away from direct sunlight. Keep the bottle tightly closed and out of reach of children.
Mefenamic Acid (Infamix) 50mg/5ml Suspension is effective for managing pain, menstrual cramps, and fever. Adhering to the prescribed dosage and usage instructions ensures efficacy and minimizes potential side effects.
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