Metoclopromide (Meclop) 5mg/ml Solution for Injection I.M/I.V 2ml x Ampoule 10's

Generic Name: Metoclopromide

Brand Name: Meclop

Strength: 5mg / 5ml

Form: Ampoule

Manufacturer:

Imported and Distributed by:

Classification: Gastrokinetics

Indication/Uses:

Metoclopramide (Meclop) 5mg/ml Solution for Injection I.M/I.V 2ml x Ampoule 10's is used for its gastrointestinal and antiemetic effects. Here are the primary indications and uses for this injectable form of metoclopramide:

Indications and Uses

1. Nausea and Vomiting:

   • Acute Management: Metoclopramide is used to control severe nausea and vomiting, particularly in cases where oral administration is not possible or practical. This includes nausea and vomiting associated with chemotherapy, postoperative recovery, or severe gastroenteritis.

2. Gastroparesis:

   • Improvement of Gastric Emptying: It is used to enhance gastric motility in patients with gastroparesis (delayed stomach emptying) which can help alleviate symptoms like nausea, vomiting, and fullness.

3. Preoperative or Postoperative Nausea:

   • Preventive Use: It can be administered to prevent or manage nausea and vomiting following surgical procedures, especially when oral medication is not feasible.

4. Gastroesophageal Reflux Disease (GERD):

   • Symptom Relief: In some cases, metoclopramide may be used to alleviate symptoms of GERD by improving motility and reducing reflux.

Dosage and Administration

• Dosage: The typical dose for adults is 10 mg to 20 mg administered as an intravenous (IV) or intramuscular (IM) injection. The frequency and total dose depend on the condition being treated and the patient’s response. For severe cases, injections may be repeated every 6-8 hours as needed, but the maximum recommended daily dose should not exceed 80 mg.
• Administration: The solution can be administered either intramuscularly or intravenously. Care should be taken to avoid rapid injection to reduce the risk of adverse effects.

Precautions

• Use in Specific Populations: Caution is advised in patients with a history of seizures, Parkinson's disease, or other movement disorders due to the potential for exacerbating these conditions.
• Short-Term Use: The use of metoclopramide should be limited to short-term treatment due to the risk of developing tardive dyskinesia with prolonged use.
• Drug Interactions: Be aware of potential interactions with other medications, especially those affecting the central nervous system.

Side Effects

• Common: Possible side effects include drowsiness, dizziness, and fatigue. Patients may also experience gastrointestinal symptoms like diarrhea.
• Serious: Serious side effects include extrapyramidal symptoms (such as tremors or rigidity), tardive dyskinesia, and severe allergic reactions. Any signs of these serious side effects should be promptly reported to a healthcare provider.

Monitoring

• Effectiveness: Monitor the patient's response to treatment, including the reduction of nausea and vomiting.
• Adverse Effects: Watch for any signs of serious adverse effects, particularly neurological symptoms, and adjust treatment as necessary.

Metoclopramide (Meclop) 5mg/ml Solution for Injection I.M/I.V 2ml x Ampoule 10's is used for the acute management of severe nausea and vomiting, as well as improving gastric motility. Proper dosing and adherence to safety guidelines are crucial for effective treatment and minimizing potential side effects.