Nystatin (Nystrin) 100,000 Units/ml (Oral Drops) Suspension 30ml

Nystatin (Nystrin) 100,000 Units/ml Oral Drops Suspension is an antifungal medication primarily used to treat and prevent fungal infections in the mouth and throat, commonly known as oral thrush. Here are the indications and uses of Nystatin (Nystrin) 100,000 Units/ml Oral Drops Suspension 30ml:

Indications and Uses of Nystatin (Nystrin) 100,000 Units/ml Oral Drops Suspension

1. Treatment of Oral Thrush (Candidiasis)

• Primary Use: Nystatin is mainly used to treat oral thrush, an infection caused by the Candida species of fungi, particularly Candida albicans.
• Symptom Relief: It helps relieve symptoms such as white patches on the tongue and inside the mouth, redness, soreness, difficulty swallowing, and a cottony feeling in the mouth.

2. Prophylactic Use

• Prevention of Fungal Infections: Nystatin can be used prophylactically to prevent oral thrush in individuals who are at high risk, such as those undergoing chemotherapy, receiving corticosteroids, or with immunocompromised conditions (e.g., HIV/AIDS).

Mechanism of Action

• Fungal Cell Membrane Disruption: Nystatin works by binding to ergosterol, a key component of fungal cell membranes. This binding disrupts the cell membrane, causing it to become porous and leading to the leakage of cellular contents, which ultimately results in the death of the fungal cell.

Administration Instructions

• Dosage: The typical dosage for Nystatin oral suspension is prescribed by a healthcare provider, commonly 1-2 ml four times daily. The exact dosage may vary based on the severity of the infection and the patient's response to the treatment.
• How to Use:
  • Shake the bottle well before each use to ensure the medication is evenly distributed.
  • Measure the prescribed amount using the dropper provided.
  • Place the suspension in the mouth, swish it around thoroughly for as long as possible (usually at least 30 seconds to 1 minute), and then swallow or spit out as directed.
  • Avoid eating or drinking immediately after using the medication to allow it to work effectively.

Safety and Precautions

• Consult a Healthcare Provider: Always use Nystatin under the guidance of a healthcare provider, especially if you have any other medical conditions or are taking other medications.
• Potential Side Effects: Common side effects include mild gastrointestinal disturbances such as nausea, diarrhea, stomach pain, and vomiting. If you experience severe side effects such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing, seek medical attention immediately.
• Allergic Reactions: If you have a known allergy to Nystatin or any of its components, do not use the medication.
• Use in Special Populations: Pregnant and breastfeeding women should use Nystatin only if clearly needed and prescribed by a healthcare provider.

Storage

• Proper Storage: Store the medication at room temperature, away from direct light and moisture. Keep the bottle tightly closed when not in use and out of reach of children.

Conclusion

Nystatin (Nystrin) 100,000 Units/ml Oral Drops Suspension 30ml is an effective antifungal treatment for oral thrush and can also be used prophylactically in individuals at high risk of developing fungal infections. Its localized action within the mouth and throat ensures targeted treatment with minimal systemic absorption, reducing the risk of widespread side effects. Always follow the healthcare provider's instructions regarding dosage and duration of treatment to ensure effective and safe use of the medication.