Omeprazole (Omebloc) 20mg Proton Pump Inhibitor Capsule 100's

Proton Pump Inhibitor

Storage Conditions:
Store at temperature not exceeding 30°C.

Sure! Here's a detailed breakdown of Omeprazole (Omebloc) 20mg Proton Pump Inhibitor Capsule 100's:

Product Description:

Omeprazole (Omebloc) 20mg is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach. Omeprazole blocks the proton pump in the stomach lining, which is responsible for the final step in acid production. By inhibiting this process, Omeprazole helps to decrease stomach acid levels, providing relief from conditions caused by excessive stomach acid production.

Each capsule contains 20mg of Omeprazole, and the pack contains 100 capsules for oral use. It is commonly used for short- and long-term treatment of acid-related disorders in the stomach and esophagus.

Indications:

Omeprazole (Omebloc 20mg) is used to treat a variety of conditions related to excessive stomach acid, including:

1. Gastroesophageal Reflux Disease (GERD):

   • GERD is a condition where stomach acid frequently flows back into the esophagus, causing irritation. Omeprazole helps relieve symptoms such as heartburn, acid regurgitation, and difficulty swallowing.

2. Peptic Ulcers (Gastric or Duodenal Ulcers):

   • Omeprazole is used to promote healing of peptic ulcers by reducing stomach acid production. It also helps prevent ulcers from coming back, particularly in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs).

3. Helicobacter pylori Eradication:

   • In combination with antibiotics, Omeprazole is used to eradicate H. pylori infection, which can cause ulcers in the stomach and duodenum.

4. Zollinger-Ellison Syndrome:

   • Omeprazole is used to treat Zollinger-Ellison Syndrome, a rare condition in which the stomach produces excessive acid due to tumors in the pancreas or duodenum.

5. Prevention of Acid Aspiration:

   • Omeprazole is sometimes used in preoperative settings to reduce stomach acid levels and prevent acid aspiration, especially in patients undergoing surgery.

Dosages:

The typical dosage of Omeprazole (Omebloc 20mg) varies based on the condition being treated. The usual doses are:

1. For GERD:

   • 20 mg once daily, taken before a meal, for 4 to 8 weeks. The duration may be extended based on the patient's response and the severity of symptoms.

2. For Peptic Ulcers:

   • 20 mg once daily for 4 to 8 weeks to heal gastric or duodenal ulcers.

   • For H. pylori eradication, Omeprazole is typically prescribed in combination with antibiotics (e.g., amoxicillin and clarithromycin), with the usual regimen being 20 mg twice daily for 7 to 14 days.

3. For Zollinger-Ellison Syndrome:

   • The dose may range from 60 mg daily, adjusted based on response. Higher doses, up to 120 mg daily, may be used for severe cases, divided into two doses.

4. For Prevention of Acid Aspiration (Preoperative Use):

   • 40 mg taken the night before surgery and/or in the morning before the procedure.

Note: Capsules should be swallowed whole, not chewed or crushed. If you have difficulty swallowing capsules, they can be opened and the contents mixed with a small amount of applesauce, but do not chew the granules.

Side Effects:

Omeprazole (Omebloc) is generally well-tolerated, but like all medications, it can cause side effects in some people. The common and serious side effects include:

Common Side Effects:

• Headache

• Abdominal pain

• Diarrhea

• Nausea

• Vomiting

• Flatulence (gas)

• Constipation

Serious Side Effects:

• Severe allergic reactions:

  • Rash, itching, or swelling (especially of the face/tongue/throat)

  • Difficulty breathing

  • Severe dizziness or fainting

• Severe stomach pain (can be a sign of a rare but serious condition called clostridium difficile-associated diarrhea).

• Kidney issues:

  • Dark urine, swelling in the legs, or unexplained weight gain (could indicate kidney problems).

• Bone fractures: Long-term use of PPIs like Omeprazole can increase the risk of fractures, particularly in older adults or those with other risk factors.

• Low magnesium levels:

  • Symptoms may include muscle spasms, irregular heartbeat, or seizures. Long-term use may lower magnesium levels in the body.

Rare Side Effects:

• Liver problems: Symptoms like jaundice (yellowing of the skin or eyes), dark urine, or unusual tiredness may indicate liver issues.

• Vitamin B12 deficiency: Long-term use of Omeprazole may interfere with the absorption of Vitamin B12.

Contraindications:

Omeprazole (Omebloc 20mg) should not be used in the following situations:

1. Hypersensitivity (Allergy):

   • If the patient has a known allergy or hypersensitivity to Omeprazole, other PPIs, or any of the components of the capsule.

2. Severe Liver Disease:

   • Omeprazole should be used with caution in patients with severe liver disease, as it may exacerbate liver problems.

3. Pregnancy:

   • Although Omeprazole is classified as Category C (i.e., there is limited evidence of harm in human pregnancy), it should be used only when absolutely necessary, and only under the guidance of a healthcare provider.

4. Breastfeeding:

   • Omeprazole is excreted in breast milk in small amounts, so it should be used with caution in breastfeeding mothers. A healthcare provider should be consulted to assess potential risks and benefits.

Precautions:

• Long-term Use: Long-term use of Omeprazole should be carefully monitored, as it can lead to deficiencies in certain vitamins and minerals, particularly Vitamin B12, and may increase the risk of bone fractures.

• Kidney Function: Patients with kidney disease should use Omeprazole with caution, especially for long periods, as there is a potential risk for kidney problems.

• Clostridium difficile Infection: Prolonged use of Omeprazole and other PPIs can increase the risk of Clostridium difficile-associated diarrhea, particularly in hospitalized patients.

• Magnesium Levels: Long-term use can result in low magnesium levels, which can lead to serious side effects like muscle spasms or irregular heart rhythms.

• Drug Interactions: Omeprazole may interact with other medications, including certain antifungals (e.g., ketoconazole), antiviral drugs, and warfarin, so patients should inform their healthcare provider about all medications they are taking.

Important Notes:

• Missed Dose: If you miss a dose of Omeprazole, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses at once to make up for a missed dose.

• Lifestyle Changes: Along with taking Omeprazole, lifestyle modifications such as avoiding spicy foods, caffeine, alcohol, and tobacco may help manage acid reflux symptoms more effectively.

Conclusion:

Omeprazole (Omebloc 20mg) is a proton pump inhibitor (PPI) that is effective for reducing stomach acid and treating a range of acid-related gastrointestinal disorders, including GERD, peptic ulcers, and Zollinger-Ellison syndrome. It is generally safe and well-tolerated but can cause side effects such as headaches, diarrhea, and, in rare cases, severe allergic reactions or kidney problems. Long-term use requires monitoring for potential deficiencies in vitamins and minerals. It should be used cautiously in pregnant or breastfeeding women, and patients should inform their healthcare providers about all medications they are taking to avoid potential interactions.