Paracetamol (Biogic) 125mg/5ml Suspension 60ml

125mg/5ml Suspension

ANALGESIC/ANTIPYRETIC

Paracetamol (Biogic) 125mg/5ml Suspension 60ml

Product Description:

Paracetamol (Biogic) 125mg/5ml Suspension is an over-the-counter analgesic and antipyretic medication, primarily used to relieve mild to moderate pain and reduce fever. This suspension is designed for pediatric use and provides an easy-to-administer liquid form for children who may have difficulty swallowing tablets or capsules. The active ingredient, Paracetamol, is widely known for its safety and efficacy in treating various conditions such as headaches, toothaches, sore throats, colds, and muscular pain, as well as fever associated with infections.

Indications:

Paracetamol (Biogic) Suspension is indicated for:

1. Pain Relief:

   • Mild to moderate pain relief in conditions such as headaches, toothaches, sore throats, and minor injuries.

   • Pain associated with muscular aches and joint pain.

2. Fever Reduction:

   • Used to reduce fever associated with common colds, influenza, and other viral or bacterial infections.

3. Post-vaccination Fever:

   • Often prescribed to alleviate fever or discomfort after vaccination in children.

Dosage and Administration:

Paracetamol (Biogic) is typically dosed based on the child’s weight and age. The following dosage guide is general and should always be confirmed by a healthcare professional:

• For Children (1-2 years):

  • Dose: 2.5 - 5 mL (125mg - 250mg) every 4-6 hours as needed.

  • Maximum dose: Do not exceed 4 doses (20mL) in 24 hours.

• For Children (2-4 years):

  • Dose: 5 mL (250mg) every 4-6 hours as needed.

  • Maximum dose: Do not exceed 4 doses (20mL) in 24 hours.

• For Children (4-6 years):

  • Dose: 5 - 7.5 mL (250mg - 375mg) every 4-6 hours as needed.

  • Maximum dose: Do not exceed 4 doses (30mL) in 24 hours.

• For Children (6-12 years):

  • Dose: 10 mL (500mg) every 4-6 hours as needed.

  • Maximum dose: Do not exceed 4 doses (40mL) in 24 hours.

• For Children (12 years and above):

  • Dose: 10-15 mL (500mg - 750mg) every 4-6 hours as needed.

  • Maximum dose: Do not exceed 4 doses (60mL) in 24 hours.

Administration:

• Shake the bottle well before use to ensure uniform suspension.

• Use the supplied measuring cup or syringe to administer the correct dose.

Side Effects:

While Paracetamol (Biogic) is generally well tolerated, some side effects may occur:

1. Common Side Effects:

   • Allergic reactions: Rash, itching, or swelling (especially of the face/tongue/throat).

   • Nausea or vomiting (rare, particularly with overdose or prolonged use).

   • Stomach upset: Mild stomach discomfort or indigestion.

2. Severe Side Effects (rare but serious):

   • Liver damage: Overuse or overdose of paracetamol can lead to liver toxicity and damage, potentially causing liver failure.

   • Kidney damage: Rare, but prolonged high doses can affect kidney function.

   • Blood disorders: Thrombocytopenia (low platelet count), leukopenia (low white blood cell count), or anemia may occur with prolonged use.

If any of the following symptoms occur, medical help should be sought immediately:

• Yellowing of the skin or eyes (indicative of liver damage).

• Unusual tiredness, dark urine, or abdominal pain.

• Severe allergic reactions, such as difficulty breathing, swelling of the face or throat, or rash.

Contraindications:

Paracetamol (Biogic) should not be used in the following cases:

1. Hypersensitivity:

   • Allergy to paracetamol or any of the ingredients in the formulation.

   • Severe skin reactions (e.g., redness, blisters, peeling).

2. Severe Liver Disease:

   • Patients with severe hepatic impairment or active liver disease, including cirrhosis, should not use paracetamol or should use it under strict medical supervision and at lower doses.

3. Severe Renal Impairment:

   • Renal failure or severe impairment of kidney function may require dose adjustments and medical supervision.

4. Chronic Alcohol Use:

   • Heavy alcohol use may increase the risk of liver damage, especially if combined with regular paracetamol use.

5. Acute Hepatic Failure:

   • Paracetamol should not be used in patients with acute hepatic failure or acute liver failure.

Precautions:

1. Overdose Risk:

   • Overdose is a serious medical emergency that requires immediate treatment, as paracetamol can cause liver toxicity at high doses.

   • Symptoms of overdose may include nausea, vomiting, loss of appetite, and abdominal pain followed by signs of liver failure, such as yellowing of the skin or eyes.

2. Chronic Use:

   • Prolonged use of paracetamol should be avoided unless directed by a healthcare provider. Long-term or excessive use can increase the risk of liver and kidney problems.

3. Alcohol Consumption:

   • It is advisable to limit or avoid alcohol intake while using paracetamol to reduce the risk of liver damage.

4. Renal or Hepatic Dysfunction:

   • Patients with existing kidney or liver problems should take paracetamol with caution and only under medical advice.

Drug Interactions:

1. Alcohol:

   • Excessive alcohol use can increase the risk of liver damage when taken with paracetamol.

2. Anticoagulants (e.g., Warfarin):

   • Chronic use of paracetamol can increase the anticoagulant effect of warfarin, potentially increasing the risk of bleeding.

3. Isoniazid:

   • The use of isoniazid (a drug for tuberculosis) can increase the risk of liver damage when used with paracetamol.

4. Other Liver Toxic Drugs:

   • Concurrent use with other liver-toxic drugs (e.g., certain antifungals, antivirals) should be monitored carefully.

Conclusion:

Paracetamol (Biogic) 125mg/5ml Suspension is an effective and safe analgesic and antipyretic medication for children, used to relieve pain and reduce fever. Proper dosing and adherence to guidelines are essential for safety, as overdose or prolonged use may cause serious liver or kidney damage. Parents and caregivers should be cautious about using this medication in children with liver or kidney conditions, and always follow the prescribed dosage. If any side effects occur or overdose is suspected, seek medical attention immediately.