Salbutamol Sulfate Ipratropium Bromide (Salresp I) 205mg/500mcg per 2.5ml x 35 Nebules

Product Description:

Salbutamol Sulfate Ipratropium Bromide (Salresp I) 205mg/500mcg per 2.5ml Nebules is a combination medication used to treat respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. It is delivered in the form of nebulizer solution contained in 35 single-dose nebules, each containing a combination of 205 mcg of Salbutamol Sulfate (a beta-2 agonist) and 500 mcg of Ipratropium Bromide (an anticholinergic agent).

• Salbutamol (also known as Albuterol) is a bronchodilator that works by relaxing the muscles in the airways, thereby opening the airways and making it easier to breathe.

• Ipratropium Bromide is an anticholinergic medication that works by inhibiting the action of acetylcholine on the muscarinic receptors in the airways, leading to bronchodilation and reduced mucus secretion.

The combined effect of these two drugs helps improve airflow, reduce wheezing, and alleviate shortness of breath in people with obstructive airway diseases.

Each nebule contains:

• 205 mcg Salbutamol Sulfate

• 500 mcg Ipratropium Bromide

• Volume: 2.5 ml per nebule

This product is typically used in the management of acute exacerbations or for the regular management of obstructive lung diseases.

Indications:

Salbutamol Sulfate Ipratropium Bromide (Salresp I) is indicated for:

• Chronic Obstructive Pulmonary Disease (COPD): To relieve symptoms such as wheezing, coughing, and shortness of breath.

• Asthma: For the treatment of acute bronchospasm in patients with asthma, particularly when other medications like short-acting beta agonists are not sufficient.

• Acute exacerbations of COPD or asthma: Inhalation therapy to relieve symptoms during sudden worsening of respiratory conditions.

• Other obstructive lung conditions: Where bronchodilation is required to relieve airflow limitation.

Dosage:

Salbutamol Sulfate Ipratropium Bromide (Salresp I) should be administered via nebulization using a nebulizer machine. The exact dosage will depend on the severity of the patient's condition and their individual response to the medication.

• Adults (including the elderly):

  • Acute exacerbation of COPD or asthma: Administer 1 nebule (2.5 mL), which contains 205 mcg Salbutamol and 500 mcg Ipratropium, via nebulizer. The treatment can be repeated every 4-6 hours, depending on the clinical need and doctor's instructions.

  • Maintenance therapy for COPD or asthma: The typical dose is 1 nebule (2.5 mL) 3-4 times a day. However, some patients may need higher doses based on their healthcare provider's assessment.

• Children (6 years and older):

  • Acute exacerbations of asthma or COPD: Usually, 1 nebule (2.5 mL), but the dose may vary based on the child's condition and the prescribing doctor's recommendation.

Important Notes:

• Administration: Nebulization should be done using a nebulizer machine, and the solution should not be injected or taken orally.

• Maximal dose: Do not exceed more than 12 nebulizer treatments per day unless directed by a healthcare professional.

Always follow the healthcare provider’s prescribed dosage instructions.

Side Effects:

Common side effects of Salbutamol Sulfate Ipratropium Bromide (Salresp I) may include:

• Dry mouth.

• Cough or throat irritation.

• Headache.

• Tremors (shaking of the hands or feet).

• Nausea.

• Dizziness or lightheadedness.

• Increased heart rate (tachycardia).

• Palpitations (sensation of a fast or irregular heartbeat).

Less common but more serious side effects may include:

• Worsening of breathing problems (paradoxical bronchospasm): Rare, but the patient may feel increased shortness of breath after using the nebulizer.

• Severe allergic reactions: Symptoms include swelling of the face, lips, tongue, or throat, difficulty breathing (anaphylaxis).

• Increased intraocular pressure: Symptoms of eye pain or blurred vision, particularly in individuals with glaucoma.

• Urinary retention: Difficulty urinating or painful urination, especially in men with enlarged prostate.

• Chest pain or irregular heartbeat: May be associated with higher doses or underlying heart conditions.

If any serious side effects occur, seek immediate medical attention.

Contraindications:

Salbutamol Sulfate Ipratropium Bromide (Salresp I) should not be used in the following conditions:

• Hypersensitivity to any ingredient in the formulation, including Salbutamol or Ipratropium.

• Allergic reactions: If there is a known history of allergic reactions to beta-agonists or anticholinergics, this medication should be avoided.

• Severe hypersensitivity to atropine or its derivatives.

• **Acute or worsening bronchospasm: If the patient experiences paradoxical bronchospasm or worsening of respiratory symptoms after using the medication, it should be discontinued.

• Narrow-angle glaucoma: Use with caution as anticholinergics like Ipratropium may worsen this condition.

• Prostatic hypertrophy or bladder neck obstruction: Due to the potential for urinary retention associated with Ipratropium.

• Severe heart disease: Use with caution in patients with a history of arrhythmias, heart disease, or hypertension, as Salbutamol can cause increased heart rate.

Precautions:

• Pregnancy: Use during pregnancy should be done only when clearly needed. Consult with a doctor before using this medication during pregnancy.

• Breastfeeding: It is unknown whether Salbutamol or Ipratropium pass into breast milk, so consult a healthcare provider before using this combination if breastfeeding.

• Children: Use in children should only be under the supervision of a doctor, and dosages should be carefully adjusted based on the child's age, weight, and clinical condition.

• Renal or Hepatic Impairment: Use with caution in patients with impaired kidney or liver function, as the clearance of the drug may be affected.

Important Note: This information provides a general overview of Salbutamol Sulfate Ipratropium Bromide (Salresp I), but individual care may differ. Always follow your healthcare provider's instructions for use and dosing. If you experience any side effects or have concerns about using the medication, contact your doctor.